Zinc sulfate (medical use)
Chemical model | |
Clinical data | |
---|---|
Trade names | Solvazinc, Micro-Zn, others |
AHFS/Drugs.com | Consumer Drug Information |
Pregnancy category |
|
Routes of administration | by mouth, intravenous |
Drug class | mineral supplement |
ATC code | |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
DrugBank | |
ChemSpider | |
UNII | |
ChEBI | |
ChEMBL | |
Chemical and physical data | |
Formula | ZnSO4 |
Molar mass | 161.47 |
3D model (JSmol) | |
| |
|
Zinc sulfate is used medically as a dietary supplement. Specifically it is used to treat zinc deficiency and to prevention the conditions in those at high risk.[1] This includes use together with oral rehydration therapy for children who have diarrhea.[2] General use is not recommended. It may be taken by mouth or by injection into a vein.[1]
Side effects may include abdominal pain, vomiting, headache, and feeling tired.[2] While normal doses are deemed safe in pregnancy and breastfeeding, the safety of larger doses is unclear.[3] Greater care should be taken in those with kidney problems.[2] Zinc is an essential mineral in people as well as other animals.[4]
The medical use of zinc sulfate began as early as the 1600s.[5] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[6] Zinc sulfate is available as a generic medication and over the counter.[1][3] The wholesale cost in the developing world is about 0.01 to 18 USD per day.[7] In the United Kingdom ten days of treatment costs the NHS about 4.32 pounds.[1]
Medical uses
The use of zinc sulfate supplements together with oral rehydration therapy decreases the number of bowel movements and the time until the children returns to normal in diarrhea.[2] It general use in this situation is thus recommended by the World Health Organization.[2]
Zinc sulfate is also an important part of parenteral nutrition.[1]
References
- 1 2 3 4 5 British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. p. 700. ISBN 9780857111562.
- 1 2 3 4 5 WHO Model Formulary 2008 (PDF). World Health Organization. 2009. p. 349-351. ISBN 9789241547659. Retrieved 8 January 2017.
- 1 2 "Zinc sulfate Use During Pregnancy | Drugs.com". www.drugs.com. Retrieved 15 January 2017.
- ↑ Council, National Research; Studies, Division on Earth and Life; Resources, Board on Agriculture and Natural; Animals, Committee on Minerals and Toxic Substances in Diets and Water for (2006). Mineral Tolerance of Animals: Second Revised Edition, 2005. National Academies Press. p. 420. ISBN 9780309096546.
- ↑ Sneader, Walter (2005). Drug Discovery: A History. John Wiley & Sons. p. 62. ISBN 9780471899792.
- ↑ "WHO Model List of Essential Medicines (19th List)" (PDF). World Health Organization. April 2015. Retrieved 8 December 2016.
- ↑ "Zinc Sulfate". International Drug Price Indicator Guide. Retrieved 8 December 2016.