ZBTB17

ZBTB17
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2LVR, 2LVT, 2LVU, 2M0D, 2M0E, 2M0F, 2N25, 2N26, 2Q81, 3M52, 4U2M, 4U2N, 5ION
Identifiers
Aliases	ZBTB17, MIZ-1, ZNF151, ZNF60, pHZ-67, zinc finger and BTB domain containing 17
External IDs	MGI: 107410 HomoloGene: 2575 GeneCards: ZBTB17
Gene location (Human) Chr. Chromosome 1 (human)[1] Band No data available Start 15,941,869 bp[1] End 15,976,132 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band No data available Start 141,444,654 bp[2] End 141,467,930 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • transcription factor activity, sequence-specific DNA binding • DNA binding • protein binding • metal ion binding • nucleic acid binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding • core promoter binding • transcription coactivator binding • transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding • transcription factor binding Cellular component • nucleus • nucleoplasm • protein-DNA complex • protein complex Biological process • positive regulation of transcription, DNA-templated • multicellular organism development • gastrulation with mouth forming second • ectoderm development • IRE1-mediated unfolded protein response • negative regulation of cell cycle • regulation of autophagy of mitochondrion • regulation of transcription, DNA-templated • transcription, DNA-templated • positive regulation of protein targeting to mitochondrion • transcription from RNA polymerase II promoter • negative regulation of cell proliferation • positive regulation of transcription from RNA polymerase II promoter • positive regulation of cell cycle arrest Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7709	22642
Ensembl	ENSG00000116809	ENSMUSG00000006215
UniProt	Q13105	Q60821
RefSeq (mRNA)	NM_001242884 NM_001287603 NM_001287604 NM_003443 NM_001324137 NM_001324138	NM_009541
RefSeq (protein)	NP_001229813 NP_001274532 NP_001274533 NP_001311066 NP_001311067 NP_003434	NP_033567
Location (UCSC)	Chr 1: 15.94 – 15.98 Mb	Chr 1: 141.44 – 141.47 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger and BTB domain-containing protein 17 is a protein that in humans is encoded by the ZBTB17 gene.^[5]

Interactions

ZBTB17 has been shown to interact with TOPBP1,^[6] Host cell factor C1^[7] and Myc.^[8][9]

References

Further reading

External links

• ZBTB17 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.