WDR45L
WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3), also known as WD repeat-containing protein 45-like is a protein that in humans is encoded by the gene.[5]
Structure and function
WIPI-3 is a member of the WIPI or SVP1 family of WD40 repeat-containing proteins. The protein contains seven WD40 repeats that are thought to fold into a beta-propeller structure that mediates protein–protein interactions, and a conserved motif for interaction with phospholipids.[5]
See also
References
Further reading
- Brandenberger R, Wei H, Zhang S, et al. (2004). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. PMID 15146197. doi:10.1038/nbt971.
- Jeffries TR, Dove SK, Michell RH, Parker PJ (2004). "PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49.". Mol. Biol. Cell. 15 (6): 2652–63. PMC 420090
. PMID 15020712. doi:10.1091/mbc.E03-10-0732.
- Proikas-Cezanne T, Waddell S, Gaugel A, et al. (2004). "WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy.". Oncogene. 23 (58): 9314–25. PMID 15602573. doi:10.1038/sj.onc.1208331.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
