Ubiquilin 4
Ubiquilin 4 is a protein in humans that is encoded by the UBQLN4 gene.[5][6][7] Ubiquilin 4 regulates proteasomal protein degradation.[8]
Similarity to Other Proteins
Human UBQLN4 shares a high degree of similarity with related ubiquilins including UBQLN1 and UBQLN2.[9]
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000160803 - Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000008604 - Ensembl, May 2017
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ "Entrez Gene: Ubiquilin 4". Retrieved 2013-06-27.
- ↑ Davidson JD, Riley B, Burright EN, Duvick LA, Zoghbi HY, Orr HT (September 2000). "Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein". Hum. Mol. Genet. 9 (15): 2305–12. PMID 11001934. doi:10.1093/oxfordjournals.hmg.a018922.
- ↑ Matsuda M, Koide T, Yorihuzi T, Hosokawa N, Nagata K (January 2001). "Molecular cloning of a novel ubiquitin-like protein, UBIN, that binds to ER targeting signal sequences". Biochem. Biophys. Res. Commun. 280 (2): 535–40. PMID 11162551. doi:10.1006/bbrc.2000.4149.
- ↑ Riley BE, Xu Y, Zoghbi HY, Orr HT (October 2004). "The effects of the polyglutamine repeat protein ataxin-1 on the UbL-UBA protein A1Up". J. Biol. Chem. 279 (40): 42290–301. PMID 15280365. doi:10.1074/jbc.M406284200.
- ↑ Marín I (March 2014). "The ubiquilin gene family: evolutionary patterns and functional insights". BMC Evol Biol. 14: 63. PMC 4230246 . PMID 24674348. doi:10.1186/1471-2148-14-63.
External links
- UBQLN4 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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