Troxacitabine

Troxacitabine
Identifiers

IUPAC name 4-amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2(1H)-one
CAS Number	145918-75-8^N
PubChem CID	151173
ChemSpider	399955^Y
UNII	60KQZ0388Y
ChEMBL	CHEMBL359164^Y
Chemical and physical data
Formula	C₈H₁₁N₃O₄
Molar mass	213.19 g/mol
3D model (JSmol)	Interactive image
SMILES O=C1/N=C(/N)\C=C/N1[C@H]2O[C@H](OC2)CO
InChI InChI=1S/C8H11N3O4/c9-5-1-2-11(8(13)10-5)6-4-14-7(3-12)15-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7-/m0/s1^Y Key:RXRGZNYSEHTMHC-BQBZGAKWSA-N^Y
^NY (what is this?) (verify)

Troxacitabine (brand name Troxatyl) is a nucleoside analogue with anticancer activity. Its use is being studied in patients with refractory lymphoproliferative diseases.^[1]

References

↑ Vose, Julie M.; Panwalkar, Amit; Belanger, Robert; Coiffier, Bertrand; Baccarani, Michele; Gregory, Stephanie A.; Facon, Thierry; Fanin, Renato; Caballero, Dolores; Ben-Yehuda, Dina; Giles, Francis (2007). "A phase II multicenter study of troxacitabine in relapsed or refractory lymphoproliferative neoplasms or multiple myeloma". Leukemia & Lymphoma. 48 (1): 39–45. doi:10.1080/10428190600909578.

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