TraJ 5' UTR
| traJ 5' UTR | |
|---|---|
 Predicted secondary structure and sequence conservation of traJ_5 | |
| Identifiers | |
| Symbol | traJ_5 |
| Rfam | RF00243 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Bacteria |
| SO | 0000204 |
The traJ 5' UTR is a cis acting RNA element which is involved in regulating plasmid transfer in bacteria.
In conjugating bacteria the FinOP system regulates the transfer of F-like plasmids. The FinP gene encodes an antisense RNA product that is complementary to part of the 5' UTR of the traJ mRNA.[1] The traJ gene encodes a protein required for transcription from the major transfer promoter, pY. The FinO protein is essential for effective repression, acting by binding to FinP and protecting it from RNase E degradation.
References
- ↑ Arthur DC, Ghetu AF, Gubbins MJ, Edwards RA, Frost LS, Glover JN (2003). "FinO is an RNA chaperone that facilitates sense-antisense RNA interactions". EMBO J. 22 (23): 6346–55. PMC 291848
. PMID 14633993. doi:10.1093/emboj/cdg607.
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