Tioxolone

Tioxolone
Names

IUPAC name 6-hydroxy-1,3-benzoxathiol-2-one
Identifiers
CAS Number	4991-65-5^N
3D model (JSmol)	Interactive image
ChemSpider	65113^N
ECHA InfoCard	100.023.321
EC Number	225-653-0
KEGG	D07211^Y
PubChem CID	72139
RTECS number	DM2953750
UNII	S0FAJ1R9CD^N
InChI InChI=1S/C7H4O3S/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3,8H^N Key: SLYPOVJCSQHITR-UHFFFAOYSA-N^N InChI=1/C7H4O3S/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3,8H Key: SLYPOVJCSQHITR-UHFFFAOYAC
SMILES C1=CC2=C(C=C1O)OC(=O)S2
Properties
Chemical formula	C₇H₄O₃S
Molar mass	168.16986
Melting point	158 to 160 °C (316 to 320 °F; 431 to 433 K)
Pharmacology
ATC code	D10AB03 (WHO)
Hazards
R-phrases (outdated)	R22, R36/37/38
S-phrases (outdated)	S26
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

Tioxolone (INN, also spelled thioxolone) is an anti-acne preparation.^[1]

References

↑ Lius, V.; Sennerfeldt, P. (1979). "Local treatment of acne with tioxolone". Lakartidningen. 76 (1–2): 39–41. PMID 153995.

Acne-treating agents (D10)
Antibacterial	Azelaic acid Benzoyl peroxide^# 8-Hydroxyquinoline Blue light therapy Tea tree oil
Keratolytic	Glycolic acid Salicylic acid^# Sulfur Benzoyl peroxide^#
Anti-inflammatory	Nicotinamide Ibuprofen^# Aspirin^# Red light therapy
Antibiotics	Clindamycin Dapsone Erythromycin Sulfacetamide Tetracyclines (Lymecycline Minocycline Doxycycline)
Hormonal	Antiandrogens Bicalutamide Cyproterone acetate Drospirenone Flutamide Spironolactone) Estrogens Estradiol Ethinylestradiol
Retinoids	Adapalene Isotretinoin Motretinide Tazarotene Tretinoin
Other	Benzamycin Epristeride Mesulfen Pelretin Stridex Tioxolone
Combinations	Adapalene/benzoyl peroxide Benzoyl peroxide/clindamycin Clindamycin/tretinoin Erythromycin/isotretinoin Sulfacetamide/sulfur
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

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