Tick-borne disease

Tick-borne disease
Classification and external resources
Specialty Infectious disease
eMedicine emerg/584
MeSH D017282

Tick-borne diseases, which afflict humans and other animals, are caused by infectious agents transmitted by tick bites. Tick-borne illnesses are caused by infection with a variety of pathogens, including rickettsia and other types of bacteria, viruses, and protozoa. Because individual ticks can harbor more than one disease-causing agent, patients can be infected with more than one pathogen at the same time, compounding the difficulty in diagnosis and treatment. As of 2016, 16 tick-borne diseases of humans are known (four discovered since 2013).

As the incidence of tick-borne illnesses increases and the geographic areas in which they are found expand, health workers increasingly must be able to distinguish the diverse, and often overlapping, clinical presentations of these diseases.

Diagnosis and treatment

In general, specific laboratory tests are not available to rapidly diagnose tick-borne diseases. Due to their seriousness, antibiotic treatment is often justified based on clinical presentation alone.

Exposure

Ticks tend to be more active during warmer months, though this varies by geographic region and climate. Areas with woods, bushes, high grass, or leaf litter are likely to have more ticks. Those bitten commonly experience symptoms such as body aches, fever, fatigue, joint pain, or rashes. People can limit their exposure to tick bites by wearing light-colored clothing (including pants and long sleeves), using insect repellent with 20%–30% DEET, tucking their pants legs into their socks, checking for ticks frequently, and washing and drying their clothing (in a hot dryer).[1][2]

Assessing risk

For a person or companion animal to acquire a tick-borne disease requires that that individual gets bitten by a tick and that that tick feeds for a sufficient period of time. The feeding time required to transmit pathogens differs for different ticks and different pathogens. Transmission of the bacterium that causes Lyme disease is well understood to require a substantial feeding period.[3]

For an individual to acquire infection, the feeding tick must also be infected. Not all ticks are infected. In most places in the US, 30-50% of deer ticks will be infected with Borrelia burgdorferi (the agent of Lyme disease). Other pathogens are much more rare. Ticks can be tested for infection using a highly specific and sensitive qPCR procedure. Several commercial labs provide this service to individuals for a fee. The Laboratory of Medical Zoology (LMZ), a nonprofit lab at the University of Massachusetts, provides a comprehensive TickReport [4] for a variety of human pathogens and makes the data available to the public.[5] Those wishing to know the incidence of tick-borne diseases in their town or state can search the LMZ surveillance database.[5]

Examples

Major tick-borne diseases include:

Bacterial

Viral

Protozoan

Toxin

See also

References

  1. "Tick-Borne Diseases". cdc.gov. Centers for Disease Control and Prevention: National Institute for Occupational Safety and Health. Retrieved May 21, 2009.
  2. Rahlenbeck, Sibylle; Fingerle, Volker; Doggett, Stephen (2016-09-01). "Prevention of tick-borne diseases: an overview". Br J Gen Pract. 66 (650): 492–494. ISSN 0960-1643. PMID 27563139. doi:10.3399/bjgp16X687013.
  3. "Tick-Encounter". Retrieved June 19, 2015.
  4. "TickReport". tickreport.com. Laboratory of Medical Zoology: University of Massachusetts.
  5. 1 2 "Tick-Borne Disease Network". tickdiseases.org. Laboratory of Medical Zoology: University of Massachusetts.
  6. Mayo Clinic Staff. "Lyme disease: Symptoms". MayoClinic.com. Diseases and Conditions. Mayo Clinic.
  7. Mayo Clinic Staff. "Lyme disease: Treatments and drugs". MayoClinic.com. Diseases and Conditions. Mayo Clinic.
  8. Relapsing fever at eMedicine.
  9. Relapsing fever~treatment at eMedicine.
  10. 1 2 3 4 Lindblom, A; Wallménius, K; Nordberg, M; Forsberg, P; et al. (2012). "Seroreactivity for spotted fever rickettsiae and co-infections with other tick-borne agents among habitants (sic) in central and southern Sweden". European Journal of Clinical Microbiology & Infectious Diseases. 32 (3): 317–23. PMC 3569577Freely accessible. PMID 22961007. doi:10.1007/s10096-012-1742-3.
  11. Beard CB, Nelson CA, Mead PS, Petersen LR (Nov 2012). "Bartonella spp. bacteremia and rheumatic symptoms in patients from Lyme disease–endemic region". Emerging Infectious Diseases. 18 (11): 1918–1919. Retrieved 21 March 2017.
  12. Janecek, Elisabeth and Andreas Mietze, Ralph Goethe, Thomas Schnieder, Christina Strube (Oct 2012). "Bartonella spp. Infection Rate and B. grahamii in Ticks". Emerging Infectious Diseases. 18 (10): 1689–1690. PMID 23017501. Retrieved 21 March 2017.
  13. Dobler, Gerhard (2010-01-27). "Zoonotic tick-borne flaviviruses". Veterinary Microbiology. Zoonoses: Advances and Perspectives. 140 (3–4): 221–228. doi:10.1016/j.vetmic.2009.08.024.
  14. "Powassan Virus | Powassan | CDC". www.cdc.gov. Retrieved 2017-06-07.
  15. Pastula, DM; Turabelidze, G; Yates, KF; Jones, TF; et al. (March 2014). "Notes from the field: Heartland virus disease - United States, 2012-2013". Morbidity and Mortality Weekly Report. 63 (12): 270–1. PMID 24670929.
  16. "Ticks". medent.usyd.edu.au. Department of Entomology, University of Sydney and Westmead Hospital. November 7, 2003.
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