TXNDC12
Thioredoxin domain-containing protein 12 is a protein that in humans is encoded by the TXNDC12 gene.[5][6][7]
TXNDC12 belongs to the thioredoxin superfamily (see TXN; MIM 187700). Members of this superfamily possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors[8] (Liu et al., 2003).[supplied by OMIM][7]
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000117862 - Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028567 - Ensembl, May 2017
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. PMID 8619474. doi:10.1006/abio.1996.0138.
- ↑ Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. PMC 139146
. PMID 9110174. doi:10.1101/gr.7.4.353. - 1 2 "Entrez Gene: TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum)".
- ↑ Galligan JJ, Petersen DR (July 2012). "The human protein disulfide isomerase gene family". Human Genomics. 6 (6). PMC 3500226 . PMID 23245351. doi:10.1186/1479-7364-6-6.
Further reading
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
- Alanen HI, Williamson RA, Howard MJ, et al. (2003). "Functional characterization of ERp18, a new endoplasmic reticulum-located thioredoxin superfamily member.". J. Biol. Chem. 278 (31): 28912–20. PMID 12761212. doi:10.1074/jbc.M304598200.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. PMC 403697 . PMID 12975309. doi:10.1101/gr.1293003.
- Liu F, Rong YP, Zeng LC, et al. (2004). "Isolation and characterization of a novel human thioredoxin-like gene hTLP19 encoding a secretory protein.". Gene. 315: 71–8. PMID 14557066. doi:10.1016/S0378-1119(03)00732-7.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285.
- Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites.". Protein Sci. 13 (10): 2819–24. PMC 2286551 . PMID 15340161. doi:10.1110/ps.04682504.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
- Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. PMID 16303743. doi:10.1093/dnares/12.2.117.
- Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature. 441 (7091): 315–21. PMID 16710414. doi:10.1038/nature04727.
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