TUBE1
TUBE1 | |||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||
Aliases | TUBE1, TUBE, dJ142L7.2, tubulin epsilon 1 | ||||||||||||||||||||||||
External IDs | MGI: 1919174 HomoloGene: 17762 GeneCards: TUBE1 | ||||||||||||||||||||||||
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Orthologs | |||||||||||||||||||||||||
Species | Human | Mouse | |||||||||||||||||||||||
Entrez | |||||||||||||||||||||||||
Ensembl | |||||||||||||||||||||||||
UniProt | |||||||||||||||||||||||||
RefSeq (mRNA) | |||||||||||||||||||||||||
RefSeq (protein) | |||||||||||||||||||||||||
Location (UCSC) | Chr 6: 112.07 – 112.09 Mb | Chr 6: 39.13 – 39.15 Mb | |||||||||||||||||||||||
PubMed search | [3] | [4] | |||||||||||||||||||||||
Wikidata | |||||||||||||||||||||||||
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Tubulin, epsilon 1 is a protein in humans that is encoded by the TUBE1 gene.[5] This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication
References
Further reading
- Chang P, Giddings TH, Winey M, Stearns T (January 2003). "Epsilon-tubulin is required for centriole duplication and microtubule organization". Nature Cell Biology. 5 (1): 71–6. PMID 12510196. doi:10.1038/ncb900.
- Zanic M, Stear JH, Hyman AA, Howard J (October 2009). May RC, ed. "EB1 recognizes the nucleotide state of tubulin in the microtubule lattice". PloS One. 4 (10): e7585. PMC 2761489 . PMID 19851462. doi:10.1371/journal.pone.0007585.
- Chang P, Stearns T (January 2000). "Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function". Nature Cell Biology. 2 (1): 30–5. PMID 10620804. doi:10.1038/71350.
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