TSPYL2

TSPYL2

Identifiers

TSPYL2, CDA1, CINAP, CTCL, DENTT, HRIHFB2216, NP79, SE204, TSPX, TSPY-like 2, TSPY like 2

External IDs

MGI: 106244 HomoloGene: 11140 GeneCards: TSPYL2

Gene location (Human)

Chr.	X chromosome (human)^[1]

Band	No data available	Start	53,082,367 bp^[1]
Band	No data available	End	53,088,540 bp^[1]

Gene location (Mouse)

Chr.	X chromosome (mouse)^[2]

Band	No data available	Start	152,336,852 bp^[2]
Band	No data available	End	152,342,425 bp^[2]

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• rDNA binding • protein binding
Cellular component	• nucleolus • nucleoplasm • nucleus • cytoplasm
Biological process	• cell cycle • nucleosome assembly • IRE1-mediated unfolded protein response • negative regulation of cell cycle • negative regulation of DNA replication • regulation of protein kinase activity • regulation of transcription, DNA-templated • regulation of signal transduction • negative regulation of cell growth • transcription, DNA-templated • covalent chromatin modification
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


64061


52808


ENSG00000184205


ENSMUSG00000041096


Q9H2G4


Q7TQI8

RefSeq (mRNA)


NM_022117


NM_029836 NM_145936

RefSeq (protein)


NP_071400


NP_084112

Location (UCSC)

Chr X: 53.08 – 53.09 Mb

Chr X: 152.34 – 152.34 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Testis-specific Y-encoded-like protein 2 is a protein that in humans is encoded by the TSPYL2 gene.^[5]^[6]^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000184205 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041096 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Ozbun LL, You L, Kiang S, Angdisen J, Martinez A, Jakowlew SB (Apr 2001). "Identification of differentially expressed nucleolar TGF-beta1 target (DENTT) in human lung cancer cells that is a new member of the TSPY/SET/NAP-1 superfamily". Genomics. 73 (2): 179–93. PMID 11318608. doi:10.1006/geno.2001.6505.
↑ Chai Z, Sarcevic B, Mawson A, Toh BH (Sep 2001). "SET-related cell division autoantigen-1 (CDA1) arrests cell growth". J Biol Chem. 276 (36): 33665–74. PMID 11395479. doi:10.1074/jbc.M007681200.
↑ "Entrez Gene: TSPYL2 TSPY-like 2".

Further reading

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMC 310948 . PMID 11076863. doi:10.1101/gr.143000.
Eichmuller S, Usener D, Dummer R, et al. (2001). "Serological detection of cutaneous T-cell lymphoma-associated antigens.". Proc. Natl. Acad. Sci. U.S.A. 98 (2): 629–34. PMC 14639 . PMID 11149944. doi:10.1073/pnas.021386498.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. PMC 311072 . PMID 11230166. doi:10.1101/gr.GR1547R.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Wang GS, Hong CJ, Yen TY, et al. (2004). "Transcriptional modification by a CASK-interacting nucleosome assembly protein.". Neuron. 42 (1): 113–28. PMID 15066269. doi:10.1016/S0896-6273(04)00139-4.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. PMC 528930 . PMID 15489336. doi:10.1101/gr.2576704.
Santama N, Ogg SC, Malekkou A, et al. (2006). "Characterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus.". J. Biol. Chem. 280 (43): 36429–41. PMID 16079131. doi:10.1074/jbc.M501982200.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. PMC 1347501 . PMID 16381901. doi:10.1093/nar/gkj139.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell. 125 (4): 801–14. PMID 16713569. doi:10.1016/j.cell.2006.03.032.
Radke JR, Donald RG, Eibs A, et al. (2006). "Changes in the expression of human cell division autoantigen-1 influence Toxoplasma gondii growth and development.". PLoS Pathog. 2 (10): e105. PMC 1626100 . PMID 17069459. doi:10.1371/journal.ppat.0020105.
Tu Y, Wu W, Wu T, et al. (2007). "Antiproliferative autoantigen CDA1 transcriptionally up-regulates p21(Waf1/Cip1) by activating p53 and MEK/ERK1/2 MAPK pathways.". J. Biol. Chem. 282 (16): 11722–31. PMID 17317670. doi:10.1074/jbc.M609623200.

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