TRANK1

TRANK1
Identifiers
AliasesTRANK1, LBA1, tetratricopeptide repeat and ankyrin repeat containing 1
External IDsMGI: 1341834 HomoloGene: 45845 GeneCards: TRANK1
Gene location (Human)
Chr.Chromosome 3 (human)[1]
BandNo data availableStart36,826,820 bp[1]
End36,945,057 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

9881

320429

Ensembl

ENSG00000168016

ENSMUSG00000062296

UniProt

O15050

Q8BV79

RefSeq (mRNA)

NM_014831
NM_001329998

NM_001164659

RefSeq (protein)

NP_001316927
NP_055646

NP_001158131

Location (UCSC)Chr 3: 36.83 – 36.95 MbChr 3: 111.31 – 111.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tetratricopeptide repeat and ankyrin repeat containing 1 is a protein that in humans is encoded by the TRANK1 gene. [5]

Disease Linkage

Through a Genome-wide association study, TRANK1 has been relationed with the Bipolar disorder.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000168016 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000062296 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: Tetratricopeptide repeat and ankyrin repeat containing 1". Retrieved 2014-06-22.
  6. ↑ "Genome-wide association study reveals two new risk loci for bipolar disorder". Nat Commun. 5: 3339. 2014. PMID 24618891. doi:10.1038/ncomms4339.

Further reading

  • Goes, F. S.; Hamshere, M. L.; Seifuddin, F; Pirooznia, M; Belmonte-Mahon, P; Breuer, R; Schulze, T; Nöthen, M; Cichon, S; Rietschel, M; Holmans, P; Zandi, P. P.; Craddock, N; Craddock, N; Potash, J. B. (2012). "Genome-wide association of mood-incongruent psychotic bipolar disorder". Translational Psychiatry. 2 (10): e180. PMC 3565814 Freely accessible. PMID 23092984. doi:10.1038/tp.2012.106. 
  • Chen, D. T.; Jiang, X; Akula, N; Shugart, Y. Y.; Wendland, J. R.; Steele, C. J.; Kassem, L; Park, J. H.; Chatterjee, N; Jamain, S; Cheng, A; Leboyer, M; Muglia, P; Schulze, T. G.; Cichon, S; Nöthen, M. M.; Rietschel, M; McMahon, F J; McMahon, F. J.; Kelsoe, J. R.; Greenwood, T. A.; Nievergelt, C. M.; McKinney, R; Shilling, P. D.; Schork, N. J.; Smith, E. N.; Bloss, C. S.; Nurnberger Jr, J. I.; Edenberg, H. J.; et al. (2013). "Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder". Molecular Psychiatry. 18 (2): 195–205. PMID 22182935. doi:10.1038/mp.2011.157. 
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