TMX1

TMX1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1X5E

Identifiers

TMX1, PDIA11, TMX, TXNDC, TXNDC1, thioredoxin related transmembrane protein 1

External IDs

MGI: 1919986 HomoloGene: 12482 GeneCards: TMX1

Gene location (Human)

Chr.	Chromosome 14 (human)^[1]

Band	No data available	Start	51,240,162 bp^[1]
Band	No data available	End	51,257,546 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 12 (mouse)^[2]

Band	No data available	Start	70,453,095 bp^[2]
Band	No data available	End	70,468,040 bp^[2]

Gene ontology
Molecular function	• disulfide oxidoreductase activity • protein disulfide isomerase activity
Cellular component	• integral component of membrane • membrane • endoplasmic reticulum membrane • endoplasmic reticulum
Biological process	• protein folding • oxidation-reduction process • response to endoplasmic reticulum stress • cell redox homeostasis
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


81542


72736


ENSG00000139921


ENSMUSG00000021072


Q9H3N1


Q8VBT0

RefSeq (mRNA)


NM_030755


NM_028339

RefSeq (protein)


NP_110382


NP_082615

Location (UCSC)

Chr 14: 51.24 – 51.26 Mb

Chr 14: 70.45 – 70.47 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Thioredoxin-related transmembrane protein 1 is a protein that in humans is encoded by the TMX1 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000139921 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021072 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Matsuo Y, Akiyama N, Nakamura H, Yodoi J, Noda M, Kizaka-Kondoh S (Mar 2001). "Identification of a novel thioredoxin-related transmembrane protein". J Biol Chem. 276 (13): 10032–8. PMID 11152479. doi:10.1074/jbc.M011037200.
↑ "Entrez Gene: TXNDC1 thioredoxin domain containing 1".

Further reading

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14.". Nature. 421 (6923): 601–7. PMID 12508121. doi:10.1038/nature01348.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. PMC 403697 . PMID 12975309. doi:10.1101/gr.1293003.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. PMC 514446 . PMID 15302935. doi:10.1073/pnas.0404720101.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. PMID 16303743. doi:10.1093/dnares/12.2.117.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. PMC 1356129 . PMID 16344560. doi:10.1101/gr.4039406.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell. 127 (3): 635–48. PMID 17081983. doi:10.1016/j.cell.2006.09.026.

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