THSD1

THSD1

Identifiers

THSD1, TMTSP, UNQ3010, thrombospondin type 1 domain containing 1

External IDs

MGI: 1929096 HomoloGene: 10264 GeneCards: THSD1

Gene location (Human)

Chr.	Chromosome 13 (human)^[1]

Band	No data available	Start	52,377,167 bp^[1]
Band	No data available	End	52,406,494 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 8 (mouse)^[2]

Band	No data available	Start	22,227,313 bp^[2]
Band	No data available	End	22,261,334 bp^[2]

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


55901


56229


ENSG00000136114


ENSMUSG00000031480


Q9NS62


Q9JM61

RefSeq (mRNA)


NM_199263 NM_018676


NM_001205253 NM_001293688 NM_019576

RefSeq (protein)


NP_061146 NP_954872


NP_001192182 NP_001280617 NP_062522

Location (UCSC)

Chr 13: 52.38 – 52.41 Mb

Chr 13: 22.23 – 22.26 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Thrombospondin type-1 domain-containing protein 1 is a protein that in humans is encoded by the THSD1 gene.^[5]

The protein encoded by this gene contains a type 1 thrombospondin domain, which is found in thrombospondin, a number of proteins involved in the complement pathway, as well as extracellular matrix proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000136114 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031480 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
1 2 "Entrez Gene: THSD1 thrombospondin, type I, domain containing 1".

Further reading

Bork P (1993). "The modular architecture of a new family of growth regulators related to connective tissue growth factor". FEBS Lett. 327 (2): 125–30. PMID 7687569. doi:10.1016/0014-5793(93)80155-N.
Gruber HE, Ingram JA, Hanley EN (2007). "Immunolocalization of thrombospondin in the human and sand rat intervertebral disc". Spine. 31 (22): 2556–61. PMID 17047544. doi:10.1097/01.brs.0000241117.31510.e3.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Orr AW, Pallero MA, Xiong WC, Murphy-Ullrich JE (2005). "Thrombospondin induces RhoA inactivation through FAK-dependent signaling to stimulate focal adhesion disassembly". J. Biol. Chem. 279 (47): 48983–92. PMID 15371459. doi:10.1074/jbc.M404881200.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. PMC 2665288 . PMID 15057823. doi:10.1038/nature02379.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. PMC 403697 . PMID 12975309. doi:10.1101/gr.1293003.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.

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