SucA RNA motif

SucA RNA motif

Identifiers
Symbol sucA
Rfam RF01070
Other data
RNA type Cis-reg
Domain(s) Bacteria
SO 0005836

The sucA RNA motif is a conserved RNA structure found in bacteria of the order Burkholderiales.[1] RNAs within this motif are always found in the presumed 5' UTR of sucA genes. sucA encodes a subunit of an enzyme that participates in the citric acid cycle by synthesizing succinyl-CoA from 2-oxoglutarate. A part of the conserved structure overlaps predicted Shine-Dalgarno sequences (involved in ribosome binding) of the downstream sucA genes. Because of the RNA motif's consistent gene association and a possible mechanism for sequestering the ribosome binding site, it was proposed that the sucA RNA motif corresponds to a cis-regulatory element. Its relatively complex secondary structure could indicate that it is a riboswitch. However, the function of this RNA motif remains unknown.

See also

References

  1. ↑ Weinberg Z, Barrick JE, Yao Z, et al. (2007). "Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline". Nucleic Acids Res. 35 (14): 4809–19. PMC 1950547 Freely accessible. PMID 17621584. doi:10.1093/nar/gkm487.


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