Sturamustine

Sturamustine
Clinical data
Synonyms N-(2-Chloroethyl)-N'-(3-hydroxyandrost-5-en-17-yl)-N-nitrosourea
Identifiers
CAS Number
ChemSpider
Chemical and physical data
Formula C22H34ClN3O3
Molar mass 423.982 g/mol
3D model (JSmol)

Sturamustine, also known as dehydroepiandrosterone (DHEA) 17β-N-(2-chloroethyl)-N-nitrosourea, is a synthetic androstane steroid and a C17β nitrosourea conjugate of dehydroepiandrosterone (DHEA) that was developed as an alkylating antineoplastic agent (i.e., a chemotherapy drug) for the treatment of hormone-dependent tumors but was never marketed.[1][2] It was synthesized in 1982.[1][2]

See also

References

  1. 1 2 J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 1122. ISBN 978-1-4757-2085-3.
  2. 1 2 Chavis C, de Gourcy C, Borgna JL, Imbach JL (1982). "New steroidal nitrosoureas". Steroids. 39 (2): 129–47. PMID 7071885.


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