Small nucleolar RNA TBR5
| Small nucleolar RNA TBR5 | |
|---|---|
 Predicted secondary structure and sequence conservation of snoTBR5 | |
| Identifiers | |
| Symbol | snoTBR5 |
| Rfam | RF00292 |
| Other data | |
| RNA type | Gene; snRNA; snoRNA; CD-box |
| Domain(s) | Eukaryota |
| GO | 0006396 0005730 |
| SO | 0000593 |
TBR5 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1][2]
References
- ↑ Galardi, S.; Fatica, A.; Bachi, A.; Scaloni, A.; Presutti, C.; Bozzoni, I. (October 2002). "Purified Box C/D snoRNPs Are Able to Reproduce Site-Specific 2'-O-Methylation of Target RNA in Vitro". Molecular and Cellular Biology. 22 (19): 6663–6668. PMC 134041
. PMID 12215523. doi:10.1128/MCB.22.19.6663-6668.2002. - ↑ Dunbar, DA; Wormsley S; Lowe TM; Baserga SJ (2000). "Fibrillarin-associated box C/D small nucleolar RNAs in Trypanosoma brucei. Sequence conservation and implications for 2'-O-ribose methylation of rRNA". J Biol Chem. 275 (19): 14767–14776. PMID 10747997. doi:10.1074/jbc.M001180200.
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