Salicylamide

Salicylamide

Clinical data
MedlinePlus	a681004
ATC code	N02BA05 (WHO) N02BA55 (WHO) (combinations)
Pharmacokinetic data
Excretion	Renal
Identifiers
IUPAC name 2-hydroxybenzamide
CAS Number	65-45-2 Y
PubChem CID	5147
DrugBank	DB08797 Y
ChemSpider	4963 Y
UNII	EM8BM710ZC
ChEBI	CHEBI:32114 Y
ChEMBL	CHEMBL27577 Y
NIAID ChemDB	018403
ECHA InfoCard	100.000.554
Chemical and physical data
Formula	C7H7NO2
Molar mass	137.136 g/mol
3D model (JSmol)	Interactive image
Density	1.33 g/cm3
Solubility in water	Soluble in hot water, ether, alcohol, and chloroform. mg/mL (20 °C)
SMILES O=C(c1ccccc1O)N
InChI InChI=1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10) Y Key:SKZKKFZAGNVIMN-UHFFFAOYSA-N Y
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Salicylamide (o-hydroxybenzamide or amide of salicyl) is a non-prescription drug with analgesic and antipyretic properties. Its medicinal uses are similar to those of aspirin.^[1] Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedy "PainAid". It was also an ingredient in the over-the-counter pain remedy BC Powder but was removed from the formulation in 2009. It was used in later formulations of Vincent's powders in Australia as a substitute for phenacetin.

Pure Salicylamide is a white or slightly pink crystalline powder

Derivatives

Salicylamide is used in the synthesis of: (or formed part of the core structure for)

Salan salicylamide derivatives are not for pain relief. They are used for antiseptic/disinfectant or anthelmintic. E.g.

1. Bensalan
2. Fursalan
3. Dibromsalan
4. Salantel
5. Metabromsalan
6. Fluorosalan
7. Tribromsalan

See also

• 4-Aminosalicylic acid
• Mesalazine
• Salsalate

References

1. ↑ salicylamide. Dictionary.com. Merriam-Webster's Medical Dictionary. Merriam-Webster, Inc. (accessed: December 31, 2006).

External links

• Safety MSDS data