SNAPC3

Identifiers

SNAPC3, PTFbeta, SNAP50, small nuclear RNA activating complex polypeptide 3

External IDs

MGI: 1916338 HomoloGene: 31130 GeneCards: SNAPC3

Gene location (Human)

Chr.	Chromosome 9 (human)^[1]

Band	No data available	Start	15,422,704 bp^[1]
Band	No data available	End	15,465,953 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 4 (mouse)^[2]

Band	No data available	Start	83,417,724 bp^[2]
Band	No data available	End	83,467,676 bp^[2]

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• protein binding • DNA binding
Cellular component	• nucleus • nucleoplasm • nucleolus • nuclear body
Biological process	• snRNA transcription • regulation of transcription, DNA-templated • transcription from RNA polymerase II promoter • transcription, DNA-templated • transcription from RNA polymerase III promoter • snRNA transcription from RNA polymerase II promoter
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


6619


77634

Ensembl


ENSG00000164975


ENSMUSG00000028483

UniProt


Q92966


Q9D2C9

RefSeq (mRNA)


NM_001039697 NM_003084


NM_029949

RefSeq (protein)


NP_001034786


NP_084225

Location (UCSC)

Chr 9: 15.42 – 15.47 Mb

Chr 9: 83.42 – 83.47 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

snRNA-activating protein complex subunit 3 is a protein that in humans is encoded by the SNAPC3 gene.^[5]^[6]

Interactions

SNAPC3 has been shown to interact with SNAPC1^[5]^[7] and Retinoblastoma protein.^[8]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000164975 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028483 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
1 2 Henry RW; Ma B; Sadowski CL; Kobayashi R; Hernandez N (February 1997). "Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc". EMBO J. 15 (24): 7129–36. PMC 452539 . PMID 9003788.
↑ "Entrez Gene: SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa".
↑ Ma, B; Hernandez N (February 2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc". J. Biol. Chem. United States. 276 (7): 5027–35. ISSN 0021-9258. PMID 11056176. doi:10.1074/jbc.M009301200.
↑ Hirsch, H A; Gu L; Henry R W (Dec 2000). "The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression". Mol. Cell. Biol. UNITED STATES. 20 (24): 9182–91. ISSN 0270-7306. PMC 102176 . PMID 11094070. doi:10.1128/MCB.20.24.9182-9191.2000.

Bagramian ER; Bogdanova EA; Krymskaia ML; Sokovykh SI (1977). "[Diagnostic importance of determining 17-ketosteroids in gynecology]". Akusherstvo i ginekologiia (2): 65–7. PMID 900378.
Henry RW; Sadowski CL; Kobayashi R; Hernandez N (1995). "A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III.". Nature. 374 (6523): 653–6. PMID 7715707. doi:10.1038/374653a0.
Bai L; Wang Z; Yoon JB; Roeder RG (1996). "Cloning and characterization of the beta subunit of human proximal sequence element-binding transcription factor and its involvement in transcription of small nuclear RNA genes by RNA polymerases II and III.". Mol. Cell. Biol. 16 (10): 5419–26. PMC 231541 . PMID 8816454.
Ma B; Hernandez N (2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc.". J. Biol. Chem. 276 (7): 5027–35. PMID 11056176. doi:10.1074/jbc.M009301200.
Hirsch HA; Gu L; Henry RW (2001). "The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression.". Mol. Cell. Biol. 20 (24): 9182–91. PMC 102176 . PMID 11094070. doi:10.1128/MCB.20.24.9182-9191.2000.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Hinkley CS, Hirsch HA, Gu L, et al. (2003). "The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition.". J. Biol. Chem. 278 (20): 18649–57. PMID 12621023. doi:10.1074/jbc.M204247200.
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature. 429 (6990): 369–74. PMC 2734081 . PMID 15164053. doi:10.1038/nature02465.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature. 437 (7062): 1173–8. PMID 16189514. doi:10.1038/nature04209.
Jawdekar GW, Hanzlowsky A, Hovde SL, et al. (2006). "The unorthodox SNAP50 zinc finger domain contributes to cooperative promoter recognition by human SNAPC.". J. Biol. Chem. 281 (41): 31050–60. PMID 16901896. doi:10.1074/jbc.M603810200.

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SNAPC3

Interactions

References

Further reading