SLAMF8

SLAMF8
Identifiers
AliasesSLAMF8, BLAME, CD353, SBBI42, SLAM family member 8
External IDsMGI: 1921998 HomoloGene: 10589 GeneCards: SLAMF8
Gene location (Human)
Chr.Chromosome 1 (human)[1]
BandNo data availableStart159,826,750 bp[1]
End159,837,249 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

56833

74748

Ensembl

ENSG00000158714

ENSMUSG00000053318

UniProt

Q9P0V8

Q9D3G2

RefSeq (mRNA)

NM_020125
NM_001330741

NM_029084

RefSeq (protein)

NP_001317670
NP_064510

NP_083360

Location (UCSC)Chr 1: 159.83 – 159.84 MbChr 1: 172.58 – 172.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SLAM family member 8 is a protein that in humans is encoded by the SLAMF8 gene.[5][6]

Function

This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000158714 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000053318 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Kingsbury GA, Feeney LA, Nong Y, Calandra SA, Murphy CJ, Corcoran JM, Wang Y, Prabhu Das MR, Busfield SJ, Fraser CC, Villeval JL (May 2001). "Cloning, expression, and function of BLAME, a novel member of the CD2 family". Journal of Immunology. 166 (9): 5675–80. PMID 11313408. doi:10.4049/jimmunol.166.9.5675.
  6. 1 2 "Entrez Gene: SLAMF8 SLAM family member 8".

Further reading

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