SEC61G

SEC61G
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2WWB, 3J7R, 4CG7, 3J7Q, 4CG5, 4CG6
Identifiers
Aliases	SEC61G, SSS1, Sec61 translocon gamma subunit
External IDs	HomoloGene: 40767 GeneCards: SEC61G
Gene location (Human) Chr. Chromosome 7 (human)[1] Band No data available Start 54,752,250 bp[1] End 54,759,974 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • P-P-bond-hydrolysis-driven protein transmembrane transporter activity • protein transporter activity • protein binding Cellular component • integral component of membrane • cytosol • endoplasmic reticulum membrane • membrane • endoplasmic reticulum Biological process • protein targeting • IRE1-mediated unfolded protein response • protein transmembrane transport • protein targeting to ER • protein transport • intracellular protein transport • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23480	n/a
Ensembl	ENSG00000132432	n/a
UniProt	P60059	n/a
RefSeq (mRNA)	NM_014302 NM_001012456	n/a
RefSeq (protein)	NP_001012474 NP_055117	n/a
Location (UCSC)	Chr 7: 54.75 – 54.76 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

Protein transport protein Sec61 subunit gamma is a protein that in humans is encoded by the SEC61G gene.^[3][4][5]

Function

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein have been identified.^[5]

References

Further reading