Cutamesine

Cutamesine

Names
IUPAC name 1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine
Identifiers
CAS Number	165377-43-5 Y 165377-44-6 (dihydrochloride) N
3D model (JSmol)	Interactive image
PubChem CID	9954941
SMILES COC1=C(OC)C=C(CCN2CCN(CCCC3=CC=CC=C3)CC2)C=C1
Properties
Chemical formula	C23H32N2O2
Molar mass	368.52 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Cutamesine (SA 4503) is a sigma receptor agonist.^[1][2][3]

References

1. ↑ Matsuno K, Nakazawa M, Okamoto K, Kawashima Y, Mita S (1996). "Binding properties of SA4503, a novel and selective sigma 1 receptor agonist". European Journal of Pharmacology. 306 (1–3): 271–9. PMID 8813641. doi:10.1016/0014-2999(96)00201-4. 
2. ↑ Skuza G, Rogóz Z (2006). "The synergistic effect of selective sigma receptor agonists and uncompetitive NMDA receptor antagonists in the forced swim test in rats". J. Physiol. Pharmacol. 57 (2): 217–29. PMID 16845227. 
3. ↑ Xu R, Lord SA, Peterson RM, Fergason-Cantrell EA, Lever JR, Lever SZ (January 2015). "Ether modifications to 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine (SA4503): effects on binding affinity and selectivity for sigma receptors and monoamine transporters.". Bioorganic & Medicinal Chemistry. 23 (1): 222–230. PMC 4274187 . PMID 25468036. doi:10.1016/j.bmc.2014.11.007. 

External links

• SA 4503 at the US National Library of Medicine Medical Subject Headings (MeSH)