Rohon-Beard cell

Zebrafish embryo 48 hours after fertilization. The arrows indicate four Rohon-Beard neurons.[1]

Rohon-Beard cells are specialized neurons with mechanoreceptive properties. They occur during the embryonic stage of development and are found in the dorsal part of the spinal cord in fish and amphibians.[2]

Rohon-Beard neurons develop on the border between the ectoderm epidermal (surface) and neuroectoderm, first in the order of receptor neurons.[3]

In most species Rohon-Beard cells disappear during the course of ontogenetic development (e.g. in zebrafish during the first two to four weeks of development, at the late larval, early juvenile stage to be, replaced by a dorsal root ganglion of spinal nerves)[4] by apoptosis.[5]

John Beard and Joseph Victor Rohon first described these cells, independently of each other.

See also

References

  1. ↑ Shimada, N.; Sokunbi, G.; Moorman, SJ. (2005). "Changes in gravitational force affect gene expression in developing organ systems at different developmental times.". BMC Dev Biol. 5: 10. PMC 1177936 Freely accessible. PMID 15927051. doi:10.1186/1471-213X-5-10.
  2. ↑ Fox, Harold (1984). Amphibian morphogenesi. Clifton, N.J.: Humana. ISBN 0-89603-043-1.
  3. ↑ Rossi, CC.; Kaji, T.; Artinger, KB. (Apr 2009). "Transcriptional control of Rohon-Beard sensory neuron development at the neural plate border.". Dev Dyn. 238 (4): 931–43. PMC 2755227 Freely accessible. PMID 19301392. doi:10.1002/dvdy.21915.
  4. ↑ Kanungo, J.; Zheng, YL.; Mishra, B.; Pant, HC. (Jun 2009). "Zebrafish Rohon-Beard neuron development: cdk5 in the midst.". Neurochem Res. 34 (6): 1129–37. PMID 19067160. doi:10.1007/s11064-008-9885-4.
  5. ↑ Reyes, R.; Haendel, M.; Grant, D.; Melancon, E.; Eisen, JS. (Jan 2004). "Slow degeneration of zebrafish Rohon-Beard neurons during programmed cell death.". Dev Dyn. 229 (1): 30–41. PMID 14699575. doi:10.1002/dvdy.10488.


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