Respirovirus
| Respirovirus | |
|---|---|
| Virus classification | |
| Group: | Group V ((−)ssRNA) |
| Order: | Mononegavirales |
| Family: | Paramyxoviridae |
| Genus: | Respirovirus |
| Type species | |
| Murine respirovirus | |
| Species | |
|
Bovine respirovirus 3 | |
Respirovirus is a genus of viruses in the order Mononegavirales, in the family Paramyxoviridae. Rodents and human serve as natural hosts. There are currently five species in this genus including the type species Sendai virus. Diseases associated with this genus include: acute febrile respiratory tract infection.[1][2]
Taxonomy
| Genus | Species | Virus (Abbreviation) | NCBI Taxonomy ID |
| Respirovirus | Bovine respirovirus 3 | bovine parainfluenza virus 3 (BPIV-3) | |
| Human respirovirus 1 | human parainfluenza virus 1 (HPIV-1) | 12730 | |
| Human respirovirus 3 | human parainfluenza virus 3 (HPIV-3) | 11216 | |
| Murine respirovirus* | Sendai virus (SeV) | 11191 | |
| Porcine respirovirus 1 | porcine parainfluenza virus 1 (PPIV-1) | ||
Table legend: "*" denotes type species.
Structure
Respirovirions are enveloped, with spherical geometries. The diameter is around 150 nm. Respirovirus genomes are linear, around 15kb in length. The genome codes for 8 proteins.[1]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Respirovirus | Spherical | Enveloped | Linear | Monopartite |
Life cycle
Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaches to host cell. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. Translation takes place by leaky scanning, and ribosomal shunting. The virus exits the host cell by budding. Rodents and human serve as the natural host. Transmission routes are respiratory.[1]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Respirovirus | Rodents; humans | None | Glycoprotein | Budding | Cytoplasm | Cytoplasm | Aerosols |
References
- 1 2 3 "Viral Zone". ExPASy. Retrieved 15 June 2015.
- ↑ ICTV. "Virus Taxonomy: 2014 Release". Retrieved 15 June 2015.
- ↑ Afonso, Claudio L.; Amarasinghe, Gaya K.; Bányai, Krisztián; Bào, Yīmíng; Basler, Christopher F.; Bavari, Sina; Bejerman, Nicolás; Blasdell, Kim R.; Briand, François-Xavier (2016-08-01). "Taxonomy of the order Mononegavirales: update 2016". Archives of Virology. 161 (8): 2351–2360. ISSN 1432-8798. PMC 4947412
. PMID 27216929. doi:10.1007/s00705-016-2880-1.