RNF122

RNF122

Identifiers

RNF122, ring finger protein 122

External IDs

MGI: 1916117 HomoloGene: 11717 GeneCards: RNF122

Gene location (Human)

Chr.	Chromosome 8 (human)^[1]

Band	No data available	Start	33,547,755 bp^[1]
Band	No data available	End	33,567,125 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 8 (mouse)^[2]

Band	No data available	Start	31,111,820 bp^[2]
Band	No data available	End	31,131,482 bp^[2]

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• ubiquitin protein ligase activity • metal ion binding
Cellular component	• integral component of membrane • Golgi apparatus • membrane • endoplasmic reticulum
Biological process	• protein ubiquitination involved in ubiquitin-dependent protein catabolic process • proteasome-mediated ubiquitin-dependent protein catabolic process • protein polyubiquitination
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


79845


68867


ENSG00000133874


ENSMUSG00000039328


Q9H9V4


Q8BP31

RefSeq (mRNA)


NM_024787


NM_175136

RefSeq (protein)


NP_079063


NP_780345

Location (UCSC)

Chr 8: 33.55 – 33.57 Mb

Chr 8: 31.11 – 31.13 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

RING finger protein 122 is a protein that in humans is encoded by the RNF122 gene.^[5]

The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000133874 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039328 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
1 2 "Entrez Gene: RNF122 ring finger protein 122".

Further reading

Koyama K, Sudo K, Nakamura Y (1995). "Isolation of 115 human chromosome 8-specific expressed-sequence tags by exon amplification". Genomics. 26 (2): 245–53. PMID 7601449. doi:10.1016/0888-7543(95)80207-3.
Saurin AJ, Borden KL, Boddy MN, Freemont PS (1996). "Does this have a familiar RING?". Trends Biochem. Sci. 21 (6): 208–14. PMID 8744354. doi:10.1016/s0968-0004(96)80017-x.
Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. PMC 16267 . PMID 10737800. doi:10.1073/pnas.97.7.3491.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. PMC 1356129 . PMID 16344560. doi:10.1101/gr.4039406.
Wang L, Gao X, Gao P, et al. (2006). "Cell-based screening and validation of human novel genes associated with cell viability". Journal of Biomolecular Screening. 11 (4): 369–76. PMID 16751333. doi:10.1177/1087057106286654.
Wang L, Shi TP, Wang L, et al. (2006). "[Cloning, expression and subcellular localization of a novel human gene-RNF122]". Beijing Da Xue Xue Bao. 38 (3): 239–43. PMID 16778963.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.