RLF (gene)

RLF

Identifiers

RLF, ZN-15L, ZNF292L, rearranged L-myc fusion

External IDs

MGI: 1924705 HomoloGene: 8243 GeneCards: RLF

Gene location (Human)

Chr.	Chromosome 1 (human)^[1]

Band	No data available	Start	40,161,373 bp^[1]
Band	No data available	End	40,240,921 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 4 (mouse)^[2]

Band	No data available	Start	121,145,373 bp^[2]
Band	No data available	End	121,215,084 bp^[2]

Gene ontology
Molecular function	• DNA binding • zinc ion binding • protein binding • metal ion binding • nucleic acid binding
Cellular component	• nucleus
Biological process	• positive regulation of transcription, DNA-templated • regulation of transcription, DNA-templated • DNA integration • chromosome organization • transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter • regulation of DNA methylation • histone H3-K4 monomethylation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


6018


109263


ENSG00000117000


ENSMUSG00000049878


Q13129


n/a

RefSeq (mRNA)


NM_012421


NM_001081013 NM_001346660

RefSeq (protein)


NP_036553


n/a

Location (UCSC)

Chr 1: 40.16 – 40.24 Mb

Chr 1: 121.15 – 121.22 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Zinc finger protein Rlf is a protein that in humans is encoded by the RLF gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000117000 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000049878 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Makela TP, Kere J, Winqvist R, Alitalo K (Aug 1991). "Intrachromosomal rearrangements fusing L-myc and rlf in small-cell lung cancer". Mol Cell Biol. 11 (8): 4015–21. PMC 361204 . PMID 1649386.
↑ "Entrez Gene: RLF rearranged L-myc fusion".

Further reading

Olsen JV; Blagoev B; Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. PMID 17081983. doi:10.1016/j.cell.2006.09.026.
Gregory SG; Barlow KF; McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. PMID 16710414. doi:10.1038/nature04727.
Swick L, Kapatos G (2006). "A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions". J. Neurochem. 97 (5): 1447–55. PMC 2239266 . PMID 16696853. doi:10.1111/j.1471-4159.2006.03836.x.
Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Colland F; Jacq X; Trouplin V; et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. PMC 442148 . PMID 15231748. doi:10.1101/gr.2334104.
Lanigan TM; Liu A; Huang YZ; et al. (2003). "Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf". FASEB J. 17 (14): 2048–60. PMID 14597674. doi:10.1096/fj.02-1096com.
Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Shao H, Kadono-Okuda K, Finlin BS, Andres DA (1999). "Biochemical characterization of the Ras-related GTPases Rit and Rin". Arch. Biochem. Biophys. 371 (2): 207–19. PMID 10545207. doi:10.1006/abbi.1999.1448.
Mäkelä TP; Hellsten E; Vesa J; et al. (1996). "The rearranged L-myc fusion gene (RLF) encodes a Zn-15 related zinc finger protein". Oncogene. 11 (12): 2699–704. PMID 8545128.

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