REEP1

REEP1

Identifiers

REEP1, C2orf23, HMN5B, SPG31, Yip2a, receptor accessory protein 1

External IDs

MGI: 1098827 HomoloGene: 41504 GeneCards: REEP1

Gene location (Human)

Chr.	Chromosome 2 (human)^[1]

Band	No data available	Start	86,213,993 bp^[1]
Band	No data available	End	86,338,083 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 6 (mouse)^[2]

Band	No data available	Start	71,707,561 bp^[2]
Band	No data available	End	71,810,710 bp^[2]

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• microtubule binding • protein binding • olfactory receptor binding
Cellular component	• cytoplasm • integral component of membrane • endoplasmic reticulum • membrane • mitochondrial membrane • mitochondrion • endoplasmic reticulum membrane • endoplasmic reticulum tubular network
Biological process	• endoplasmic reticulum tubular network organization • protein insertion into membrane • regulation of intracellular transport
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


65055


52250


ENSG00000068615


ENSMUSG00000052852


Q9H902


Q8BGH4

RefSeq (mRNA)


NM_001164730 NM_001164731 NM_001164732 NM_022912


NM_178608

RefSeq (protein)


NP_001158202 NP_001158203 NP_001158204 NP_075063


NP_848723

Location (UCSC)

Chr 2: 86.21 – 86.34 Mb

Chr 2: 71.71 – 71.81 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Receptor expression-enhancing protein 1 is a protein that in humans is encoded by the REEP1 gene.^[5]^[6]^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000068615 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000052852 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Clark AJ, Metherell LA, Cheetham ME, Huebner A (Nov 2005). "Inherited ACTH insensitivity illuminates the mechanisms of ACTH action". Trends Endocrinol Metab. 16 (10): 451–7. PMID 16271481. doi:10.1016/j.tem.2005.10.006.
↑ Saito H, Kubota M, Roberts RW, Chi Q, Matsunami H (Nov 2004). "RTP family members induce functional expression of mammalian odorant receptors". Cell. 119 (5): 679–91. PMID 15550249. doi:10.1016/j.cell.2004.11.021.
↑ "Entrez Gene: REEP1 receptor accessory protein 1".

Further reading

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285.
Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain.". Mol. Cell Proteomics. 3 (11): 1093–101. PMID 15345747. doi:10.1074/mcp.M400085-MCP200.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature. 434 (7034): 724–31. PMID 15815621. doi:10.1038/nature03466.
Behrens M, Bartelt J, Reichling C, et al. (2006). "Members of RTP and REEP gene families influence functional bitter taste receptor expression.". J. Biol. Chem. 281 (29): 20650–9. PMID 16720576. doi:10.1074/jbc.M513637200.
Züchner S, Wang G, Tran-Viet KN, et al. (2006). "Mutations in the novel mitochondrial protein REEP1 cause hereditary spastic paraplegia type 31.". Am. J. Hum. Genet. 79 (2): 365–9. PMC 1559498 . PMID 16826527. doi:10.1086/505361.

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