Proline rich 5 like

PRR5L

Identifiers

PRR5L, PROTOR2, proline rich 5 like

External IDs

MGI: 1919696 HomoloGene: 11753 GeneCards: PRR5L

Gene location (Human)

Chr.	Chromosome 11 (human)^[1]

Band	No data available	Start	36,296,288 bp^[1]
Band	No data available	End	36,465,204 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 2 (mouse)^[2]

Band	No data available	Start	101,714,285 bp^[2]
Band	No data available	End	101,883,027 bp^[2]

Gene ontology
Molecular function	• ubiquitin protein ligase binding • protein binding
Cellular component	• TORC2 complex • mitochondrion
Biological process	• TORC2 signaling • negative regulation of protein phosphorylation • positive regulation of phosphatidylinositol 3-kinase signaling • negative regulation of signal transduction • positive regulation of protein phosphorylation • regulation of fibroblast migration • cellular response to oxidative stress • positive regulation of mRNA catabolic process • positive regulation of intracellular protein transport
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


79899


72446


ENSG00000135362


ENSMUSG00000032841


Q6MZQ0


A2AVJ5

RefSeq (mRNA)


NM_024841 NM_001160167 NM_001160168 NM_001160169


NM_001083810 NM_001110849 NM_175181

RefSeq (protein)


NP_001153639 NP_001153640 NP_001153641 NP_079117


NP_001077279 NP_001104319 NP_780390

Location (UCSC)

Chr 11: 36.3 – 36.47 Mb

Chr 11: 101.71 – 101.88 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Proline rich 5 like is a protein that in humans is encoded by the PRR5L gene. ^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000135362 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032841 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ "Entrez Gene: Proline rich 5 like". Retrieved 2017-03-17.

Further reading

Pearce LR, Huang X, Boudeau J, Pawłowski R, Wullschleger S, Deak M, Ibrahim AF, Gourlay R, Magnuson MA, Alessi DR (2007). "Identification of Protor as a novel Rictor-binding component of mTOR complex-2". Biochem. J. 405 (3): 513–22. PMC 2267312 . PMID 17461779. doi:10.1042/BJ20070540.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ (2010). "Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression". PLoS ONE. 5 (9): e12862. PMC 2943476 . PMID 20877624. doi:10.1371/journal.pone.0012862.

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