Marginal nucleus of spinal cord

Posteromarginal nucleus
Medulla spinalis (Rexed lamina I labeled at upper left.)
Details
Identifiers
Latin	Nucleus marginalis medullae spinalis, lamina spinalis I
NeuroNames	ancil-984
TA	A14.1.02.117
FMA	68862
*Anatomical terms of neuroanatomy*

The marginal nucleus of spinal cord, or posteromarginal nucleus, or Substantia Marginalis, Rexed lamina I, is located at the most dorsal aspect of the dorsal horn of the spinal cord. The neurons located here receive input primarily from Lissauer's tract and relay information related to pain and temperature sensation. Pain sensation relayed here cannot be modulated, e.g. pain from burning the skin.

The spinal cord

General features

Grey matter

Posterior grey column	Marginal nucleus Substantia gelatinosa of Rolando Nucleus proprius Spinal lamina V Spinal lamina VI
Lateral grey column	Intermediolateral nucleus Posterior thoracic nucleus
Anterior grey column	Interneuron Alpha motor neuron Onuf's nucleus Gamma motor neuron
Other	Rexed laminae Central gelatinous substance Gray commissure Central canal Terminal ventricle

White matter

Sensory

Posterior	Posterior column-medial lemniscus pathway: Gracile Cuneate
Lateral:	Spinocerebellar dorsal ventral Spinothalamic lateral anterior Posterolateral Spinotectal
Spinoreticular tract Spino-olivary tract

Motor

Lateral	Corticospinal Lateral Extrapyramidal Rubrospinal Olivospinal Raphespinal
Anterior	Corticospinal Anterior Extrapyramidal Vestibulospinal Reticulospinal Tectospinal

Both

Anterior white commissure

External features

Ventral
- Anterior median fissure
- Anterolateral sulcus
Dorsal
- Posterior median sulcus
- Posterolateral sulcus

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