Pinaverium

Pinaverium

Clinical data
ATC code	A03AX04 (WHO)
Identifiers
IUPAC name 4-(2-bromo-4,5-dimethoxybenzyl)-4-(2-[2-(6,6-dimethylbicyclo[3.1.1]heptan-2-yl)ethoxy]ethyl)morpholin-4-ium
CAS Number	59995-65-2 Y
PubChem CID	40704
ChemSpider	37182
UNII	U2368VVE7O
Chemical and physical data
Formula	C26H41BrNO4
Molar mass	511.51 g/mol
3D model (JSmol)	Interactive image
SMILES CC1(C2CCC(C1C2)CCOCC[N+]3(CCOCC3)CC4=CC(=C(C=C4Br)OC)OC)C
InChI InChI=1S/C26H41BrNO4/c1-26(2)21-6-5-19(22(26)16-21)7-11-31-12-8-28(9-13-32-14-10-28)18-20-15-24(29-3)25(30-4)17-23(20)27/h15,17,19,21-22H,5-14,16,18H2,1-4H3/q+1 Key:DDHUTBKXLWCZCO-UHFFFAOYSA-N
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Pinaverium is a drug used for functional gastrointestinal disorders. It belongs to a drug group call antispasmodic and acts as a calcium channel blocker in helping to restore the normal contraction process of the bowel. It is most effective when taken for a full course of treatment and is not designed for immediate symptom relief or sporadic, intermittent use.

Pinaverium was first registered in 1975 by Solvay Pharmaceuticals (now a division of Abbott Laboratories), and marketed globally using the brand names Dicetel and Eldicet. Generic pinaverium is available in South Korea under a trade name of Disten^[1], and in Argentina as Nulite^[2].

Indications

It is indicated for the treatment and relief of symptoms associated with irritable bowel syndrome (IBS): abdominal pain, bowel disturbances and intestinal discomfort; and treatment of symptoms related to functional disorders of biliary tract.^[3]

References