Phyllocladan-16alpha-ol synthase

Phyllocladan-16alpha-ol synthase
Identifiers
EC number 4.2.3.45
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Phyllocladan-16alpha-ol synthase (EC 4.2.3.45, PaDC1) is an enzyme with systematic name (+)-copalyl-diphosphate diphosphate-lyase (phyllocladan-16alpha-ol-forming).[1] This enzyme catalyses the following chemical reaction

(+)-copalyl diphosphate + H2O phyllocladan-16alpha-ol + diphosphate

The adjacent gene PaDC2 codes EC 5.5.1.12, copalyl diphosphate synthase.

References

  1. Toyomasu, T.; Niida, R.; Kenmoku, H.; Kanno, Y.; Miura, S.; Nakano, C.; Shiono, Y.; Mitsuhashi, W.; Toshima, H.; Oikawa, H.; Hoshino, T.; Dairi, T.; Kato, N.; Sassa, T. (2008). "Identification of diterpene biosynthetic gene clusters and functional analysis of labdane-related diterpene cyclases in Phomopsis amygdali". Biosci. Biotechnol. Biochem. 72: 1038–1047. PMID 18391465. doi:10.1271/bbb.70790.
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