Paul Lieberman
Paul M. Lieberman, Ph.D., is a researcher and director of the Center for Chemical Biology and Translational Medicine at The Wistar Institute in Philadelphia.[1][2][3][4] He is also the Hilary Koprowski, M.D., Endowed Professor, the McNeil Professor of Molecular Medicine and Translational Research , a professor in the Gene Expression and Regulation Program , and the Scientific Director of the Protein Expression and Libraries Facility at Wistar. Lieberman's research focus is how certain viruses are linked to cancer, particularly Epstein-Barr virus.
Lieberman and his laboratory collaborated with Memorial Sloan-Kettering Cancer Center to develop the first annotated atlas of the genome of Epstein-Barr virus.[5] In 2011, Liberman received a Seeding Drug Discovery Award from Wellcome Trust for $4.7 million to develop a drug against Epstein-Barr virus-related cancers. This was the first project to receive such an award from the United Kingdom-based trust.[6] Lieberman serves as the president of the International Association for Research on Epstein-Barr virus and Associated Diseases.[7]
Select publications
- Deng Z, Glousker G, et al., Lieberman PM, Tzfati, Y. Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome. PNAS 2013.
- Dheekollu J, Chen HS, Kaye KM, Lieberman PM. Timeless-dependent DNA replication-coupled recombination promotes Kaposi’s Sarcoma-associated herpesvirus episome maintenance and terminal repeat stability. J. Virology. 2013 Apr 87(7):369.
- Deng Z, Wang Z, Stong N, Plasschaert R, et al. Riethman H, and Lieberman PM. A role for CTCF and cohesion in subtelomere chromatin organization, TERRA transcription, and telomere end protection. EMBO J. 2012 Nov 31(21):4165.
- Kang H, Cho H, Sung GH, Lieberman PM. CTCF regulates Kaposi’s sarcoma-associated herpesvirus latency transcription by nucleosome displacement and RNA polymerase programming. Journal of Virology 2013 Feb 87(3)1789.
- Arvey A, Tempera I, Tsai K, Chen HS, Tikhmyanova N, Klichinsky M, Leslie C, Lieberman PM. An atlas of the Epstein-Barr virus transcriptome and epigenome reveals host-virus regulatory interactions. Cell Host Microbe 2012 Aug 12(2)233.
References
- ↑ "Paul M. Lieberman, Ph.D.". The Wistar Institute. Retrieved 17 February 2014.
- ↑ "Paul M. Lieberman, Ph.D.". The University of Pennsylvania. Retrieved 17 February 2014.
- ↑ "Management". Vironika. Retrieved 17 February 2014.
- ↑ "The Wistar Institute and University of the Sciences Announce McNeil Professorship to Lead Collaborative Center". Newswise. Retrieved 17 February 2014.
- ↑ "Field guide to the Epstein-Barr virus charts viral paths toward cancer". ScienceDaily. Retrieved 17 February 2014.
- ↑ "WISTAR ENTERS A $4.7 MILLION AGREEMENT TO DEVELOP DRUG AGAINST EPSTEIN-BARR VIRUS". The Wistar Institute. Retrieved 17 February 2014.
- ↑ "EBV Association Officers". Baylor College of Medicine. Retrieved 17 February 2014.