PRPSAP1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2C4K

Identifiers

Aliases

PRPSAP1, PAP39, phosphoribosyl pyrophosphate synthetase-associated protein 1, phosphoribosyl pyrophosphate synthetase associated protein 1

External IDs

MGI: 1915013 HomoloGene: 55687 GeneCards: PRPSAP1

Gene location (Human)

Chr.	Chromosome 17 (human)^[1]

Band	No data available	Start	76,309,486 bp^[1]
Band	No data available	End	76,384,521 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 11 (mouse)^[2]

Band	No data available	Start	116,470,845 bp^[2]
Band	No data available	End	116,494,202 bp^[2]

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• enzyme inhibitor activity • ribose phosphate diphosphokinase activity • magnesium ion binding • protein binding • identical protein binding
Cellular component	• ribose phosphate diphosphokinase complex • protein complex
Biological process	• nucleotide biosynthetic process • nucleobase-containing compound metabolic process • negative regulation of catalytic activity
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


5635


67763

Ensembl


ENSG00000161542


ENSMUSG00000015869

UniProt


Q14558


Q9D0M1

RefSeq (mRNA)


NM_002766 NM_001330503


NM_026364

RefSeq (protein)


NP_001317432 NP_002757


NP_080640

Location (UCSC)

Chr 17: 76.31 – 76.38 Mb

Chr 17: 116.47 – 116.49 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Phosphoribosyl pyrophosphate synthetase-associated protein 1 is an enzyme that in humans is encoded by the PRPSAP1 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000161542 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000015869 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Ishizuka T, Ahmad I, Kita K, Sonoda T, Ishijima S, Sawa K, Suzuki N, Tatibana M (Jan 1997). "The human phosphoribosylpyrophosphate synthetase-associated protein 39 gene (PRPSAP1) is located in the chromosome region 17q24-q25". Genomics. 33 (2): 332–4. PMID 8660991. doi:10.1006/geno.1996.0207.
↑ "Entrez Gene: PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1".

Tatibana M, Kita K, Taira M, et al. (1995). "Mammalian phosphoribosyl-pyrophosphate synthetase.". Adv. Enzyme Regul. 35: 229–49. PMID 7572345. doi:10.1016/0065-2571(94)00017-W.
Kita K, Ishizuka T, Ishijima S, et al. (1994). "A novel 39-kDa phosphoribosylpyrophosphate synthetase-associated protein of rat liver. Cloning, high sequence similarity to the catalytic subunits, and a negative regulatory role.". J. Biol. Chem. 269 (11): 8334–40. PMID 8132556.
Ishizuka T, Kita K, Sonoda T, et al. (1996). "Cloning and sequencing of human complementary DNA for the phosphoribosylpyrophosphate synthetase-associated protein 39.". Biochim. Biophys. Acta. 1306 (1): 27–30. PMID 8611620. doi:10.1016/0167-4781(96)00030-9.
Ishijima S, Asai T, Kita K, et al. (1997). "Partial reconstitution of mammalian phosphoribosylpyrophosphate synthetase in Escherichia coli cells. Coexpression of catalytic subunits with the 39-kDa associated protein leads to formation of soluble multimeric complexes of various compositions.". Biochim. Biophys. Acta. 1342 (1): 28–36. PMID 9366267. doi:10.1016/s0167-4838(97)00077-0.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature. 437 (7062): 1173–8. PMID 16189514. doi:10.1038/nature04209.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. PMC 1847948 . PMID 17353931. doi:10.1038/msb4100134.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

PRPSAP1

References

Further reading