PRPF40A

PRPF40A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPRPF40A, FBP-11, FBP11, FLAF1, FNBP3, HIP-10, HIP10, HYPA, NY-REN-6, Prp40, pre-mRNA processing factor 40 homolog A
External IDsMGI: 1860512 HomoloGene: 6377 GeneCards: PRPF40A
Gene location (Human)
Chr.Chromosome 2 (human)[1]
BandNo data availableStart152,651,593 bp[1]
End152,717,997 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

55660

56194

Ensembl

ENSG00000196504

ENSMUSG00000061136

UniProt

O75400

Q9R1C7

RefSeq (mRNA)

NM_017892

NM_018785

RefSeq (protein)

NP_060362

NP_061255

Location (UCSC)Chr 2: 152.65 – 152.72 MbChr 2: 53.13 – 53.19 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Pre-mRNA-processing factor 40 homolog A is a protein that in humans is encoded by the PRPF40A gene.[5][6][7]

Interactions

PRPF40A has been shown to interact with Huntingtin.[8]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000196504 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000061136 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. Bedford MT, Reed R, Leder P (Sep 1998). "WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif". Proc Natl Acad Sci U S A. 95 (18): 10602–7. PMC 27941Freely accessible. PMID 9724750. doi:10.1073/pnas.95.18.10602.
  6. Wiesner S, Stier G, Sattler M, Macias MJ (Dec 2002). "Solution structure and ligand recognition of the WW domain pair of the yeast splicing factor Prp40". J Mol Biol. 324 (4): 807–22. PMID 12460579. doi:10.1016/S0022-2836(02)01145-2.
  7. "Entrez Gene: PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)".
  8. Faber, P W; Barnes G T; Srinidhi J; Chen J; Gusella J F; MacDonald M E (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Hum. Mol. Genet. ENGLAND. 7 (9): 1463–74. ISSN 0964-6906. PMID 9700202. doi:10.1093/hmg/7.9.1463.

Further reading


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