PLRG1

PLRG1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPLRG1, Cwc1, PRL1, PRP46, PRPF46, TANGO4, pleiotropic regulator 1
External IDsMGI: 1858197 HomoloGene: 2004 GeneCards: PLRG1
Gene location (Human)
Chr.Chromosome 4 (human)[1]
BandNo data availableStart154,535,006 bp[1]
End154,550,435 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

5356

53317

Ensembl

ENSG00000171566

ENSMUSG00000027998

UniProt

O43660

Q922V4

RefSeq (mRNA)

NM_002669
NM_001201564

NM_016784

RefSeq (protein)

NP_001188493
NP_002660

NP_058064

Location (UCSC)Chr 4: 154.54 – 154.55 MbChr 4: 83.06 – 83.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Pleiotropic regulator 1 is a protein that in humans is encoded by the PLRG1 gene.[5]

Interactions

PLRG1 has been shown to interact with CDC5L.[6][7][8][9]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000171566 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027998 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: PLRG1 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)".
  6. ↑ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. England. 3 (1): 89. PMC 1847948 Freely accessible. PMID 17353931. doi:10.1038/msb4100134.
  7. ↑ Ajuh P, Lamond AI (November 2003). "Identification of peptide inhibitors of pre-mRNA splicing derived from the essential interaction domains of CDC5L and PLRG1". Nucleic Acids Res. England. 31 (21): 6104–16. PMC 275459 Freely accessible. PMID 14576297. doi:10.1093/nar/gkg817.
  8. ↑ Ajuh P, Sleeman J, Chusainow J, Lamond AI (November 2001). "A direct interaction between the carboxyl-terminal region of CDC5L and the WD40 domain of PLRG1 is essential for pre-mRNA splicing". J. Biol. Chem. United States. 276 (45): 42370–81. ISSN 0021-9258. PMID 11544257. doi:10.1074/jbc.M105453200.
  9. ↑ Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, Lamond AI (2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19 (23): 6569–81. PMC 305846 Freely accessible. PMID 11101529. doi:10.1093/emboj/19.23.6569.

Further reading


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