PLEKHB2

PLEKHB2

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3AJ4, 3VIA

Identifiers

PLEKHB2, EVT2, pleckstrin homology domain containing B2

External IDs

MGI: 2385825 HomoloGene: 9938 GeneCards: PLEKHB2

Gene location (Human)

Chr.	Chromosome 2 (human)^[1]

Band	No data available	Start	131,104,847 bp^[1]
Band	No data available	End	131,353,709 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 1 (mouse)^[2]

Band	No data available	Start	34,849,976 bp^[2]
Band	No data available	End	34,879,580 bp^[2]

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• protein binding • phosphatidylinositol-3,4,5-trisphosphate binding
Cellular component	• membrane • recycling endosome membrane • endosome • integral component of membrane
Biological process	• regulation of cell differentiation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


55041


226971


ENSG00000115762


ENSMUSG00000026123


Q96CS7


Q9QZC7

RefSeq (mRNA)

NM_001031706 NM_001100623 NM_001267062 NM_001267063 NM_001267064
NM_001267065 NM_001267066 NM_001267067 NM_001267068 NM_001309448 NM_001309450 NM_001309451 NM_001309452 NM_017958


NM_145516 NM_175421

RefSeq (protein)

NP_001094093 NP_001253991 NP_001253992 NP_001253993 NP_001253994
NP_001253995 NP_001253996 NP_001253997 NP_001296377 NP_001296379 NP_001296380 NP_001296381 NP_060428 NP_001094093.1


NP_663491 NP_780630

Location (UCSC)

Chr 2: 131.1 – 131.35 Mb

Chr 2: 34.85 – 34.88 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Pleckstrin homology domain-containing family B member 2 is a protein that in humans is encoded by the PLEKHB2 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000115762 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000026123 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Krappa R, Nguyen A, Burrola P, Deretic D, Lemke G (May 1999). "Evectins: vesicular proteins that carry a pleckstrin homology domain and localize to post-Golgi membranes". Proc Natl Acad Sci U S A. 96 (8): 4633–8. PMC 16384 . PMID 10200314. doi:10.1073/pnas.96.8.4633.
↑ "Entrez Gene: PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2".

Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene. 138 (1-2): 171–4. PMID 8125298. doi:10.1016/0378-1119(94)90802-8.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene. 200 (1-2): 149–56. PMID 9373149. doi:10.1016/S0378-1119(97)00411-3.
Dowler S, Currie RA, Campbell DG, et al. (2001). "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.". Biochem. J. 351 (Pt 1): 19–31. PMC 1221362 . PMID 11001876. doi:10.1042/0264-6021:3510019.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315–23. PMC 442147 . PMID 15231747. doi:10.1101/gr.2122004.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324–32. PMC 442148 . PMID 15231748. doi:10.1101/gr.2334104.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. PMC 1847948 . PMID 17353931. doi:10.1038/msb4100134.

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