PCGF1

PCGF1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4HPL, 4HPM

Identifiers

PCGF1, 2010002K04Rik, NSPC1, RNF3A-2, RNF68, polycomb group ring finger 1

External IDs

MGI: 1917087 HomoloGene: 13090 GeneCards: PCGF1

Gene location (Human)

Chr.	Chromosome 2 (human)^[1]

Band	No data available	Start	74,505,043 bp^[1]
Band	No data available	End	74,508,580 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 6 (mouse)^[2]

Band	No data available	Start	83,077,869 bp^[2]
Band	No data available	End	83,080,855 bp^[2]

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• protein C-terminus binding • protein binding • metal ion binding
Cellular component	• PcG protein complex • nucleus • nucleoplasm
Biological process	• histone H2A monoubiquitination • transcription, DNA-templated • regulation of transcription, DNA-templated
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


84759


69837


ENSG00000115289


ENSMUSG00000069678


Q9BSM1


Q8R023

RefSeq (mRNA)


NM_032673


NM_197992

RefSeq (protein)


NP_116062


NP_932109

Location (UCSC)

Chr 2: 74.51 – 74.51 Mb

Chr 2: 83.08 – 83.08 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Polycomb group RING finger protein 1 is a protein that in humans is encoded by the PCGF1 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000115289 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000069678 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Nunes M, Blanc I, Maes J, Fellous M, Robert B, McElreavey K (Apr 2001). "NSPc1, a novel mammalian Polycomb gene, is expressed in neural crest-derived structures of the peripheral nervous system". Mech Dev. 102 (1–2): 219–22. PMID 11287196. doi:10.1016/S0925-4773(01)00288-X.
↑ "Entrez Gene: PCGF1 polycomb group ring finger 1".

Further reading

Valk-Lingbeek ME, Bruggeman SW, van Lohuizen M (2004). "Stem cells and cancer; the polycomb connection". Cell. 118 (4): 409–18. PMID 15315754. doi:10.1016/j.cell.2004.08.005.
Gong Y, Yue J, Wu X, et al. (2007). "NSPc1 is a cell growth regulator that acts as a transcriptional repressor of p21Waf1/Cip1 via the RARE element". Nucleic Acids Res. 34 (21): 6158–69. PMC 1693893 . PMID 17088287. doi:10.1093/nar/gkl834.
Gearhart MD, Corcoran CM, Wamstad JA, Bardwell VJ (2006). "Polycomb Group and SCF Ubiquitin Ligases Are Found in a Novel BCOR Complex That Is Recruited to BCL6 Targets". Mol. Cell. Biol. 26 (18): 6880–9. PMC 1592854 . PMID 16943429. doi:10.1128/MCB.00630-06.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. PMID 16189514. doi:10.1038/nature04209.
Gong Y, Wang X, Liu J, et al. (2005). "NSPc1, a mainly nuclear localized protein of novel PcG family members, has a transcription repression activity related to its PKC phosphorylation site at S183". FEBS Lett. 579 (1): 115–21. PMID 15620699. doi:10.1016/j.febslet.2004.11.056.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.

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