Oleoyl-(acyl-carrier-protein) hydrolase

acyl-ACP thioesterase
Identifiers
EC number 3.1.2.14
CAS number 68009-83-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14) is an enzyme that catalyzes the chemical reaction

oleoyl-[acyl-carrier-protein] + H2O [acyl-carrier-protein] + oleate

Thus, the two substrates of this enzyme are [[oleoyl-[acyl-carrier-protein]]] and H2O, whereas its two products are acyl-carrier-protein and oleate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is oleoyl-[acyl-carrier-protein] hydrolase. Other names in common use include acyl-[acyl-carrier-protein] hydrolase, acyl-ACP-hydrolase, acyl-acyl carrier protein hydrolase, oleoyl-ACP thioesterase, and oleoyl-acyl carrier protein thioesterase. This enzyme participates in fatty acid biosynthesis.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2OWN and 2PFF.

References

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