OLA1

OLA1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesOLA1, DOC45, GBP45, GTBP9, GTPBP9, PTD004, Obg-like ATPase 1, Obg like ATPase 1
External IDsMGI: 1914309 HomoloGene: 5361 GeneCards: OLA1
Gene location (Human)
Chr.Chromosome 2 (human)[1]
BandNo data availableStart174,072,447 bp[1]
End174,248,698 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

29789

67059

Ensembl

ENSG00000138430

ENSMUSG00000027108

UniProt

Q9NTK5

Q9CZ30

RefSeq (mRNA)

NM_013341
NM_001011708
NM_001328688

NM_025942
NM_030091

RefSeq (protein)

NP_001011708
NP_001315617
NP_037473

NP_080218
NP_084367

Location (UCSC)Chr 2: 174.07 – 174.25 MbChr 2: 73.09 – 73.22 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Obg-like ATPase 1 is an enzyme that in humans is encoded by the OLA1 gene.[5][6] Ola1 belongs to the protein family of Obg-like GTPases but defines an exceptional example of a protein that has evolved altered nucleotide specificity and binds adenosine triphosphate (ATP) with higher affinity than guanosine triphosphate (GTP).[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000138430 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027108 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. 1 2 Koller-Eichhorn R, Marquardt T, Gail R, Wittinghofer A, Kostrewa D, Kutay U, Kambach C (Jul 2007). "Human OLA1 defines an ATPase subfamily in the Obg family of GTP-binding proteins". J Biol Chem. 282 (27): 19928–37. PMID 17430889. doi:10.1074/jbc.M700541200.
  6. "Entrez Gene: GTPBP9 GTP-binding protein 9 (putative)".

Further reading


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