Nuclear factor I

Nuclear factor I (NF-I) is a family of closely related transcription factors. They constitutively bind as dimers to specific sequences of DNA with high affinity.[1] Family members contain an unusual DNA binding domain that binds to the recognition sequence 5'-TTGGCXXXXXGCCAA-3'.[2]

Subtypes include:

References

  1. ↑ Blomquist P, Belikov S, Wrange O (January 1999). "Increased nuclear factor 1 binding to its nucleosomal site mediated by sequence-dependent DNA structure". Nucleic Acids Res. 27 (2): 517–25. PMC 148209 Freely accessible. PMID 9862974. doi:10.1093/nar/27.2.517.
  2. ↑ Walter F. Boron (2003). Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. pp. 125–126. ISBN 1-4160-2328-3.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.