Norgestomet

Norgestomet
Identifiers
Synonyms 17α-Hydroxy-11β-methyl-19-norpregn-4-ene-3,20-dione acetate
CAS Number
PubChem CID
ChemSpider
UNII
ECHA InfoCard 100.042.359
Chemical and physical data
Formula C23H32O4
Molar mass 372.49778 g/mol
3D model (JSmol)

Norgestomet (INN, USAN, BAN) (brand name Syncro-Mate B; former developmental code name SC-21009), or norgestamet, also known as 11β-methyl-17α-acetoxy-19-norprogesterone, is a steroidal progestin of the 19-norprogesterone group used in veterinary medicine to control estrus and ovulation in cattle.[1][2] It was developed and introduced in the mid-1970s.[3] In addition to the progesterone receptor, norgestomet possesses weak (micromolar) affinity for the glucocorticoid receptor.[4]

See also

References

  1. J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 887–. ISBN 978-1-4757-2085-3.
  2. Charles G. Gebelein; Richard L. Dunn (1 July 1990). Progress in Biomedical Polymers. Springer Science & Business Media. pp. 356–. ISBN 978-0-306-43523-2.
  3. I. Gordon (22 October 2013). Controlled Breeding in Farm Animals. Elsevier. pp. 40–. ISBN 978-1-4832-8569-6.
  4. Moffatt RJ, Zollers WG, Welshons WV, Kieborz KR, Garverick HA, Smith MF (1993). "Basis of norgestomet action as a progestogen in cattle". Domest. Anim. Endocrinol. 10 (1): 21–30. PMID 8467644.


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