NRK (gene)

NRK

Identifiers

NRK, NESK, Nik related kinase

External IDs

MGI: 1351326 HomoloGene: 8442 GeneCards: NRK

Gene location (Human)

Chr.	X chromosome (human)^[1]

Band	No data available	Start	105,822,543 bp^[1]
Band	No data available	End	105,958,610 bp^[1]

Gene location (Mouse)

Chr.	X chromosome (mouse)^[2]

Band	No data available	Start	138,914,430 bp^[2]
Band	No data available	End	139,010,532 bp^[2]

Gene ontology
Molecular function	• transferase activity • nucleotide binding • protein kinase activity • ATP binding • kinase activity • protein serine/threonine kinase activity • MAP kinase kinase kinase kinase activity
Cellular component	• cytoplasm
Biological process	• protein phosphorylation • activation of JNKK activity • regulation of spongiotrophoblast cell proliferation • parturition • phosphorylation • negative regulation of cell proliferation • activation of MAPKKK activity • regulation of mitotic cell cycle • stress-activated protein kinase signaling cascade • regulation of apoptotic process • neuron projection morphogenesis
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


203447


27206


ENSG00000123572


ENSMUSG00000052854


Q7Z2Y5


Q9R0G8

RefSeq (mRNA)


NM_198465


NM_013724

RefSeq (protein)


NP_940867


NP_038752

Location (UCSC)

Chr X: 105.82 – 105.96 Mb

Chr X: 138.91 – 139.01 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Nik-related protein kinase is an enzyme that is encoded by the NRK gene in humans.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000123572 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000052854 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ "Entrez Gene: NRK Nik related kinase".

Further reading

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. PMC 310948 . PMID 11076863. doi:10.1101/gr.143000.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. PMC 311072 . PMID 11230166. doi:10.1101/gr.GR1547R.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Nakano K, Kanai-Azuma M, Kanai Y, et al. (2003). "Cofilin phosphorylation and actin polymerization by NRK/NESK, a member of the germinal center kinase family". Exp. Cell Res. 287 (2): 219–27. PMID 12837278. doi:10.1016/S0014-4827(03)00136-8.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. PMC 528930 . PMID 15489336. doi:10.1101/gr.2576704.
Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. PMC 2665286 . PMID 15772651. doi:10.1038/nature03440.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. PMC 1347501 . PMID 16381901. doi:10.1093/nar/gkj139.

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