NOP58

Identifiers

NOP58, NOP5, NOP5/HSPC120, NOP58 ribonucleoprotein

External IDs

MGI: 1933184 HomoloGene: 7024 GeneCards: NOP58

Gene location (Human)

Chr.	Chromosome 2 (human)^[1]

Band	No data available	Start	202,265,716 bp^[1]
Band	No data available	End	202,303,666 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 1 (mouse)^[2]

Band	No data available	Start	59,684,971 bp^[2]
Band	No data available	End	59,719,044 bp^[2]

Gene ontology
Molecular function	• ATPase binding • protein binding • TFIID-class transcription factor binding • snoRNA binding • RNA binding
Cellular component	• small-subunit processome • Cajal body • pre-snoRNP complex • membrane • intracellular ribonucleoprotein complex • nucleoplasm • nucleolus • nucleus • box C/D snoRNP complex • small nucleolar ribonucleoprotein complex • fibrillar center • cytosol
Biological process	• ribosome biogenesis • snoRNA localization • cell growth • rRNA processing • rRNA modification
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


51602


55989

Ensembl


ENSG00000055044


ENSMUSG00000026020

UniProt


Q9Y2X3


Q6DFW4

RefSeq (mRNA)


NM_015934


NM_018868

RefSeq (protein)


NP_057018


NP_061356

Location (UCSC)

Chr 2: 202.27 – 202.3 Mb

Chr 2: 59.68 – 59.72 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Nucleolar protein 58 is a protein that in humans is encoded by the NOP58 gene.^[5]^[6]^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000055044 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000026020 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Lyman SK, Gerace L, Baserga SJ (Jan 2000). "Human Nop5/Nop58 is a component common to the box C/D small nucleolar ribonucleoproteins". RNA. 5 (12): 1597–604. PMC 1369881 . PMID 10606270. doi:10.1017/S1355838299991288.
↑ Nelson SA, Santora KE, LaRochelle WJ (Sep 2000). "Isolation and characterization of a novel PDGF-induced human gene". Gene. 253 (1): 87–93. PMID 10925205. doi:10.1016/S0378-1119(00)00232-8.
↑ "Entrez Gene: NOP5/NOP58 nucleolar protein NOP5/NOP58".

Pintard L, Kressler D, Lapeyre B (2000). "Spb1p Is a Yeast Nucleolar Protein Associated with Nop1p and Nop58p That Is Able To Bind S-Adenosyl-l-Methionine In Vitro". Mol. Cell. Biol. 20 (4): 1370–81. PMC 85287 . PMID 10648622. doi:10.1128/MCB.20.4.1370-1381.2000.
Yang Y, Isaac C, Wang C, et al. (2000). "Conserved Composition of Mammalian Box H/ACA and Box C/D Small Nucleolar Ribonucleoprotein Particles and Their Interaction with the Common Factor Nopp140". Mol. Biol. Cell. 11 (2): 567–77. PMC 14794 . PMID 10679015. doi:10.1091/mbc.11.2.567.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. PMC 310934 . PMID 11042152. doi:10.1101/gr.140200.
Verheggen C, Lafontaine DL, Samarsky D, et al. (2002). "Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments". EMBO J. 21 (11): 2736–45. PMC 126019 . PMID 12032086. doi:10.1093/emboj/21.11.2736.
Watkins NJ, Dickmanns A, Lührmann R (2003). "Conserved Stem II of the Box C/D Motif Is Essential for Nucleolar Localization and Is Required, Along with the 15.5K Protein, for the Hierarchical Assembly of the Box C/D snoRNP". Mol. Cell. Biol. 22 (23): 8342–52. PMC 134055 . PMID 12417735. doi:10.1128/MCB.22.23.8342-8352.2002.
Scherl A, Couté Y, Déon C, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. PMC 133617 . PMID 12429849. doi:10.1091/mbc.E02-05-0271.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Watkins NJ, Lemm I, Ingelfinger D, et al. (2005). "Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex". Mol. Cell. 16 (5): 789–98. PMID 15574333. doi:10.1016/j.molcel.2004.11.012.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. PMID 15635413. doi:10.1038/nature03207.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. PMID 16189514. doi:10.1038/nature04209.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. PMC 1459365 . PMID 16565220. doi:10.1073/pnas.0507066103.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. PMID 17081983. doi:10.1016/j.cell.2006.09.026.

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NOP58

References

Further reading