NFRKB

NFRKB

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3U21, 4UF6, 4WLP

Identifiers

NFRKB, INO80G, nuclear factor related to kappaB binding protein

External IDs

MGI: 2442410 HomoloGene: 4492 GeneCards: NFRKB

Gene location (Human)

Chr.	Chromosome 11 (human)^[1]

Band	No data available	Start	129,863,636 bp^[1]
Band	No data available	End	129,895,590 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 9 (mouse)^[2]

Band	No data available	Start	31,386,192 bp^[2]
Band	No data available	End	31,421,333 bp^[2]

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• protease binding • DNA binding • protein binding
Cellular component	• nucleus • Ino80 complex • nucleoplasm
Biological process	• DNA recombination • inflammatory response • regulation of transcription, DNA-templated • transcription from RNA polymerase II promoter • DNA repair • transcription, DNA-templated • cellular response to DNA damage stimulus • protein deubiquitination
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


4798


235134


ENSG00000170322


ENSMUSG00000042185


Q6P4R8


Q6PIJ4

RefSeq (mRNA)


NM_001143835 NM_006165


NM_172766

RefSeq (protein)


NP_001137307 NP_006156 NP_001137307.1


NP_766354

Location (UCSC)

Chr 11: 129.86 – 129.9 Mb

Chr 11: 31.39 – 31.42 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Nuclear factor related to kappa-B-binding protein is a protein that in humans is encoded by the NFRKB gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000170322 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042185 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Adams BS, Leung K, Meltzer PS, Lewis KA, Wagner-McPherson C, Evans GA, Nabel GJ (Dec 1992). "Localization of the gene encoding R kappa B (NFRKB), a tissue-specific DNA binding protein, to chromosome 11q24-q25". Genomics. 14 (2): 270–4. PMID 1427843. doi:10.1016/S0888-7543(05)80216-2.
↑ "Entrez Gene: NFRKB nuclear factor related to kappaB binding protein".

Further reading

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. PMID 17081983. doi:10.1016/j.cell.2006.09.026.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. PMC 1459365 . PMID 16565220. doi:10.1073/pnas.0507066103.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. PMC 514446 . PMID 15302935. doi:10.1073/pnas.0404720101.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Urban MB, Schreck R, Baeuerle PA (1991). "NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit". EMBO J. 10 (7): 1817–25. PMC 452856 . PMID 2050119.
Adams BS, Leung KY, Hanley EW, Nabel GJ (1992). "Cloning of R kappa B, a novel DNA-binding protein that recognizes the interleukin-2 receptor alpha chain kappa B site". New Biol. 3 (11): 1063–73. PMID 1777480.

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