''N'',''N''-Diisopropylaminoethanol

N,N-Diisopropylaminoethanol
Names
Preferred IUPAC name
2-[Di(propan-2-yl)amino]ethan-1-ol
Other names
2-[Di(propan-2-yl)amino]ethanol
2-(Diisopropylamino)ethanol
Identifiers
3D model (JSmol)
1697955
ChemSpider
ECHA InfoCard 100.002.307
EC Number 202-536-2
MeSH 2-diisopropylaminoethanol
RTECS number KK5950000
UN number 2922
Properties
C8H19NO
Molar mass 145.25 g·mol−1
Appearance Colorless liquid
Odor Ammoniacal
Density 826 mg mL−1
Melting point −39.2 °C; −38.6 °F; 233.9 K
Boiling point 190.1 °C; 374.1 °F; 463.2 K
log P 1.476
Vapor pressure <100 Pa (at 20 °C)
1.442
Hazards
GHS pictograms
H302, H311, H314, H331
P261, P280, P305+351+338, P310
NFPA 704
Flammability code 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g., canola oil Health code 2: Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury. E.g., chloroform Reactivity code 1: Normally stable, but can become unstable at elevated temperatures and pressures. E.g., calcium Special hazards (white): no codeNFPA 704 four-colored diamond
1
2
1
Flash point 64 °C (147 °F; 337 K)
Lethal dose or concentration (LD, LC):
  • 394 mg kg−1 (dermal, rabbit)
  • 860 mg kg−1 (oral, rat)
Related compounds
Related alkanols
Related compounds
 Diethylhydroxylamine
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

N,N-Diisopropylaminoethanol (DIPA) is a processor for production of various chemicals and also an intermediate in the production of the nerve agents VX and NX. [1] It is a clear, colorless to pale yellow liquid which has ammonia-like odor.

Health effects

Inhalation and skin contact are expected to be the primary ways of occupational exposure to this chemical. Based on single exposure animal tests, it is considered to be slightly toxic if swallowed or inhaled, moderately toxic if absorbed through skin as well as being corrosive to eyes and skin. Vapor may be irritating to the eyes and upper respiratory tract. Temporary and reversible visual disturbances characterized by mildly blurred vision, a blue-gray discolorization of sight (blue haze) or halo vision (appearance of a halo when looking at light sources) may also occur.

References

  1. ↑ Suzuki, Osamu; Kanako Watanabe, eds. (2005). Drugs and poisons in humans : a handbook of practical analysis (1. Aufl. ed.). Berlin [u.a.]: Springer. pp. 69–90. ISBN 978-3-540-22277-4.
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