Myoblast city

Myoblast city (Mbc[1]) is the Drosophila melanogaster ortholog of the mammalian protein Dock180.[2] Mutant mbc embryos exhibit defects in dorsal closure, cytoskeletal organization, myogenesis, and neural development.[2][3]

References

  1. "FlyBase Gene Report:Dmel\mbc". FlyBase Consortium. Retrieved February 25, 2009.
  2. 1 2 Erickson MR, Galletta BJ, Abmayr SM (August 1997). "Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization". J. Cell Biol. 138 (3): 589–603. PMC 2141626Freely accessible. PMID 9245788. doi:10.1083/jcb.138.3.589.
  3. Nolan KM, Barrett K, Lu Y, Hu KQ, Vincent S, Settleman J (November 1998). "Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes". Genes Dev. 12 (21): 3337–42. PMC 317223Freely accessible. PMID 9808621. doi:10.1101/gad.12.21.3337.


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