Mycobacterium arupense

Mycobacterium arupense is a rapidly growing mycobacterium first isolated from soil and human sputum samples in Spain. Etymology: arupense, pertaining to the ARUP Institute for Clinical and Experimental Pathology, where the type strain was characterized.

Description

Microscopy

• Gram-positive, nonmotile and acid-fast rods (1-3 µm x 0.5-0.7 µm), mostly strong acid-fast.

Colony characteristics

• Colonies are eugonic, rough and nonpigmented.

Physiology

• Colonies occur within 5 days at 30°C (optimum temperature, no growth at 45°C) on Löwenstein-Jensen medium and on Middlebrook 7H10 agar.
• No growth on MacConkey agar without crystal violet.
• The type strain is resistant to D-cycloserine, streptomycin, isoniazid (0.1 and 1 mg/l), rifampin, and thiacetazone and is susceptible to isoniazid (10 mg/l), kanamycin, and capreomycin.

Pathogenesis

There are emerging reports of human pathogenesis caused by Mycobacterium arupense. Pulmonary infection and tenosynovitis have been documented. A recent case of recurrent soft tissue abscess caused by Mycobacterium arupense has been identified.

Type strain

• First isolated from water samples, from soil and human sputum samples, Spain.
• Strain AR30097 = ATCC BAA-1242 = DSM 44942.

References

• CLOUD (J.L.), MEYER (J.J.), POUNDER (J.I.), JOST Jr. (K.C.), SWEENEY (A.), CARROLL (K.C.) and WOODS (G.L.): Mycobacterium arupense sp. nov., a non-chromogenic bacterium isolated from clinical specimens. Int. J. Syst. Evol. Microbiol., 2006, 56, 1413-1418.

External links

• Type strain of Mycobacterium arupense at BacDive - the Bacterial Diversity Metadatabase