Membrane estrogen receptor

Membrane estrogen receptors (mERs) are a group of receptors which bind estrogen.[1][2] Unlike the estrogen receptor (ER), a nuclear receptor which mediates its effects via genomic mechanisms, mERs are cell surface receptors which rapidly alter cell signaling via modulation of intracellular signaling cascades.[1] Putative mERs include membrane-associated ERα (mERα) and ERβ (mERβ), GPER (GPR30), ER-X, ERx, and Gq-mER.[1][2]

See also

References

  1. 1 2 3 Soltysik K, Czekaj P (April 2013). "Membrane estrogen receptors - is it an alternative way of estrogen action?". J. Physiol. Pharmacol. 64 (2): 129–42. PMID 23756388.
  2. 1 2 Micevych PE, Kelly MJ (2012). "Membrane estrogen receptor regulation of hypothalamic function". Neuroendocrinology. 96 (2): 103–10. PMC 3496782 Freely accessible. PMID 22538318. doi:10.1159/000338400.



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