Matthias Mann

Matthias Mann after a lecture in Zürich 2012

Matthias Mann (born 10 October 1959) is a scientist in the area of mass spectrometry and proteomics. Born in Germany he studied mathematics and physics at the University of Göttingen. He received his Ph.D. in 1988 at Yale University where he worked in the group of John Fenn, who was later awarded the Nobel Prize in Chemistry. After a postdoctoral fellowship at the University of Southern Denmark in Odense he became group leader at the European Molecular Biology Laboratory (EMBL) in Heidelberg. Later he went back to Odense as a professor of bioinformatics. Since 2005 he has been a director at the Max Planck Institute of Biochemistry in Munich. In addition, he will also become a principal investigator at the newly founded "Novo Nordisk Foundation Center for Protein Research" in Copenhagen.

His work has impact in various fields of mass spectrometry-based proteomics:

  • The peptide sequence tag approach developed at the EMBL was one of the first methods for the identification of peptides based on mass spectra and genome data.
  • Nano-electrospray (an electrospray technique with very low flow rates) was the first method that allowed femtomole sequencing of proteins from polyacrylamide gels.
  • A recently developed metabolic labeling technique called SILAC (stable isotope labeling with amino acids in cell culture) is widely used in quantitative proteomics.

Awards and honors

References

  1. "Ernst Schering Prize". Ernst Schering Foundation. Retrieved 16 January 2015.
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