María Blasco Marhuenda

María Blasco Marhuenda
Born 1965 (age 51–52)
Alicante, Spain
Citizenship Spain
Nationality Spanish
Fields Molecular biology
Institutions Centro Nacional de Investigaciones Oncológicas
Alma mater Universidad Autónoma de Madrid
Notable awards EMBO Gold Medal (2004)

María Antonia Blasco Marhuenda (born 1965), known as María Blasco, is a Spanish molecular biologist. She is the current director of the Spanish National Centre for Cancer Research (Centro Nacional de Investigaciones Oncológicas).

Life

Blasco was born in 1965. She obtained her PhD in 1993 for her research at the Centro de Biología Molecular Severo Ochoa (UAM-CSIC), under the supervision of Margarita Salas. That same year, Blasco joined the Cold Spring Harbor Laboratory in New York (USA) as a Postdoctoral Fellow under the leadership of Carol W. Greider. In 1997 she returned to Spain to start her own research at the Centro Nacional de Biotecnología in Madrid. She joined the Centro Nacional de Investigaciones Oncológicas](CNIO) in 2003 as Director of the Molecular Oncology Programme and Leader of the Telomeres and Telomerase Group. In 2005 she was also assigned as Vice-Director of Basic Research and in 2011 she was appointed as CNIO Director.[1][2]

Research

Professional experience

Honours and awards

Publications

More than 200 articles, see MA Blasco at Google Scholar

References

  1. ↑ "Biosketch: María A. Blasco at CNIO". CNIO.
  2. ↑ La investigadora María Blasco sustituye a Barbacid al frente del CNIO, 22/6/2011 - El País
  3. ↑ Blasco, MA; Funk W; Villaponteau B; Greider CW (1995). "Functional characterization and developmental regulation of mouse telomerase RNA component.". Science. 269: 1267–1270. doi:10.1126/science.7544492.
  4. ↑ Blasco, MA; Lee H-W; Hande P; Samper E; Lansdorp P; DePinho R; Greider CW (1997). "Telomere shortening and tumor formation by mouse cells lacking telomerase RNA.". Cell. 91: 25–34. PMID 9335332. doi:10.1016/s0092-8674(01)80006-4.
  5. ↑ Blasco, MA; Garcia-Cao, M.; O'Sullivan, R.; Peters, A.H.; Jenuwein, T. (2004). "Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases". Nature Genetics. 36 (1): 94–99. doi:10.1038/ng1278.
  6. ↑ Schoeftner, S.; Blasco, MA (2008). "Developmentally regulated transcription of mammalian telomeres by DNA dependent RNA polymerase II". Nature Cell Biology. 10 (2): 228–236. PMID 18157120. doi:10.1038/ncb1685.
  7. ↑ Benetti, R.; García-Cao, M.; Blasco, MA (2007). "Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres". Nature Genetics. 39 (2): 243–250. PMID 17237781. doi:10.1038/ng1952.
  8. ↑ Flores, I.; Canela, A.; Vera, E.; Tejera, A.; Cotsarelis, G.; Blasco, MA (2008). "The longest telomeres: a general signature of adult stem cell compartments". Genes & Development. 22: 654–667. PMC 2259034 Freely accessible. PMID 18283121. doi:10.1101/gad.451008.
  9. ↑ Tomas, A.; Flores, I.; Fernandez-Marcos, P.; Cayuela, M.L; Maraver, A.; Tejera, A.; Borras, C.; Matheu, A.; Klatt, P.; Flores, J.M.; Viña, J.; Serrano, M.; Blasco, MA (November 2008). "Telomerase reverse transcriptase delays aging in cancer resistant mice". Cell. 135 (4): 609–622. PMID 19013273. doi:10.1016/j.cell.2008.09.034.
  10. ↑ arion, R.M.; Strati, K.; Li, H.; Murga, M.; Blanco, R.; Ortega, S.; Fernandez-Capetillo, O.; Serrano, M.; Blasco, MA (August 2009). "A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity.". Nature. 460 (7259): 1149–1153. PMID 19668189. doi:10.1038/nature08287.
  11. ↑ Martinez, P.; Thanasoula, M.; Muñoz, P.; Liao, C.; Tejera, A.; McNees, C.; Flores, J.M.; Fernández-Capetillo, O.; Tarsounas, M.; Blasco, MA (2009). "Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice". Genes Dev. 23: 2060–2075. PMC 2751970 Freely accessible. PMID 19679647. doi:10.1101/gad.543509.
  12. ↑ Blasco, M. A. A. (2005). "Mice with bad ends: Mouse models for the study of telomeres and telomerase in cancer and aging". The EMBO Journal. 24 (6): 1095–1103. PMC 556402 Freely accessible. PMID 15775986. doi:10.1038/sj.emboj.7600598.
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